Establishment and Characterization of a Pair of Patient-derived Human Non-small Cell Lung Cancer Cell Lines from a Primary Tumor and Corresponding Lymph Node Metastasis.

Gebauer, Florian; Wicklein, Daniel; Tachezy, Michael; Grob, Tobias; Steinemann, Doris; Manukjan, Georgi; Göhring, Gudrun; Schlegelberger, Brigitte; Maar, Hanna; Izbicki, Jakob R; Bockhorn, Maximilian; Schumacher, Udo

Gebauer, Florian; Wicklein, Daniel; Tachezy, Michael; Grob, Tobias; Steinemann, Doris; Manukjan, Georgi; Göhring, Gudrun; Schlegelberger, Brigitte; Maar, Hanna; Izbicki, Jakob R; Bockhorn, Maximilian; Schumacher, Udo.

Afiliação

Gebauer F; Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University of Hamburg, Hamburg, Germany fgebauer@uke.de.
Wicklein D; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University of Hamburg, Hamburg, Germany.
Tachezy M; Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany.
Grob T; Institute for Pathology, University Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany.
Steinemann D; Institute of Human Genetics, Hannover Medical School, Hannover, Germany.
Manukjan G; Institute of Human Genetics, Hannover Medical School, Hannover, Germany.
Göhring G; Institute of Human Genetics, Hannover Medical School, Hannover, Germany.
Schlegelberger B; Institute of Human Genetics, Hannover Medical School, Hannover, Germany.
Maar H; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University of Hamburg, Hamburg, Germany.
Izbicki JR; Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany.
Bockhorn M; Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany.
Schumacher U; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University of Hamburg, Hamburg, Germany.

Anticancer Res ; 36(4): 1507-18, 2016 Apr.

Article em En | MEDLINE | ID: mdl-27069126

Assuntos

Carcinoma Pulmonar de Células não Pequenas; Linhagem Celular Tumoral; Neoplasias Pulmonares; Animais; Biomarcadores Tumorais/genética; Biomarcadores Tumorais/metabolismo; Carcinoma Pulmonar de Células não Pequenas/genética; Carcinoma Pulmonar de Células não Pequenas/metabolismo; Feminino; Regulação Neoplásica da Expressão Gênica; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/metabolismo; Metástase Linfática/genética; Proteínas de Membrana/metabolismo; Camundongos; Camundongos Knockout; Pessoa de Meia-Idade; Fenótipo

Palavras-chave

CD44; EGFR; EpCAM; KRAS; Non-small cell lung cancer; P-selectin; cell line; chromosomal aberrations; epithelial mesenchymal transition; integrin alpha V; lymph node metastases

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Linhagem Celular Tumoral / Neoplasias Pulmonares Limite: Animals / Female / Humans / Middle aged Idioma: En Revista: Anticancer Res Ano de publicação: 2016 Tipo de documento: Article

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