Your browser doesn't support javascript.
loading
Structural brain correlates of adolescent resilience.
Burt, Keith B; Whelan, Robert; Conrod, Patricia J; Banaschewski, Tobias; Barker, Gareth J; Bokde, Arun L W; Bromberg, Uli; Büchel, Christian; Fauth-Bühler, Mira; Flor, Herta; Galinowski, André; Gallinat, Juergen; Gowland, Penny; Heinz, Andreas; Ittermann, Bernd; Mann, Karl; Nees, Frauke; Papadopoulos-Orfanos, Dimitri; Paus, Tomas; Pausova, Zdenka; Poustka, Luise; Rietschel, Marcella; Robbins, Trevor W; Smolka, Michael N; Ströhle, Andreas; Schumann, Gunter; Garavan, Hugh.
Afiliação
  • Burt KB; Department of Psychology, University of Vermont, Burlington, VT, USA. Keith.Burt@uvm.edu.
  • Whelan R; Department of Psychology, University College Dublin, Dublin, Ireland.
  • Conrod PJ; Institute of Psychiatry, King's College London, London, UK.
  • Banaschewski T; Department of Psychiatry, CHU Ste Justine Hospital, Université de Montréal, Montreal, QC, Canada.
  • Barker GJ; Department of Cognitive and Clinical Neuroscience, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Bokde AL; Institute of Psychiatry, King's College London, London, UK.
  • Bromberg U; Institute of Neuroscience and Discipline of Psychiatry, School of Medicine, Trinity College Dublin, Dublin, Ireland.
  • Büchel C; Universitaetsklinikum Hamburg Eppendorf, Hamburg, Germany.
  • Fauth-Bühler M; Universitaetsklinikum Hamburg Eppendorf, Hamburg, Germany.
  • Flor H; Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Galinowski A; Department of Cognitive and Clinical Neuroscience, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Gallinat J; Institut National de la Santé et de la Recherche Médicale, INSERM CEA Unit 1000 'Imaging & Psychiatry', University Paris Sud, Orsay, France.
  • Gowland P; AP-HP Department of Adolescent Psychopathology and Medicine, Maison de Solenn, University Paris Descartes, Paris, France.
  • Heinz A; Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Ittermann B; School of Physics and Astronomy, University of Nottingham, Nottingham, UK.
  • Mann K; Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Nees F; Physikalisch-Technische Bundesanstalt (PTB), Braunschweig, Germany.
  • Papadopoulos-Orfanos D; Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Paus T; Department of Cognitive and Clinical Neuroscience, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Pausova Z; Neurospin, Commissariat à l'Energie Atomique et aux Energies Alternatives, Paris, France.
  • Poustka L; Rotman Research Institute, University of Toronto, Toronto, ON, Canada.
  • Rietschel M; School of Psychology, University of Nottingham, Nottingham, UK.
  • Robbins TW; Montreal Neurological Institute, McGill University, Montréal, QC, Canada.
  • Smolka MN; The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
  • Ströhle A; Department of Child and Adolescent Psychiatry and Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Schumann G; Department of Cognitive and Clinical Neuroscience, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Garavan H; Department of Experimental Psychology, Behavioural and Clinical Neurosciences Institute, University of Cambridge, Cambridge, UK.
J Child Psychol Psychiatry ; 57(11): 1287-1296, 2016 11.
Article em En | MEDLINE | ID: mdl-27079174
BACKGROUND: Despite calls for integration of neurobiological methods into research on youth resilience (high competence despite high adversity), we know little about structural brain correlates of resilient functioning. The aim of the current study was to test for brain regions uniquely associated with positive functioning in the context of adversity, using detailed phenotypic classification. METHODS: 1,870 European adolescents (Mage  = 14.56 years, SDage  = 0.44 years, 51.5% female) underwent MRI scanning and completed behavioral and psychological measures of stressful life events, academic competence, social competence, rule-abiding conduct, personality, and alcohol use. RESULTS: The interaction of competence and adversity identified two regions centered on the right middle and superior frontal gyri; grey matter volumes in these regions were larger in adolescents experiencing adversity who showed positive adaptation. Differences in these regions among competence/adversity subgroups were maintained after controlling for several covariates and were robust to alternative operationalization decisions for key constructs. CONCLUSIONS: We demonstrate structural brain correlates of adolescent resilience, and suggest that right prefrontal structures are implicated in adaptive functioning for youth who have experienced adversity.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Psicológico / Adaptação Psicológica / Córtex Pré-Frontal / Resiliência Psicológica Tipo de estudo: Prognostic_studies Limite: Adolescent / Female / Humans / Male País/Região como assunto: Europa Idioma: En Revista: J Child Psychol Psychiatry Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Psicológico / Adaptação Psicológica / Córtex Pré-Frontal / Resiliência Psicológica Tipo de estudo: Prognostic_studies Limite: Adolescent / Female / Humans / Male País/Região como assunto: Europa Idioma: En Revista: J Child Psychol Psychiatry Ano de publicação: 2016 Tipo de documento: Article