Transcriptomic gene-network analysis of exposure to silver nanoparticle reveals potentially neurodegenerative progression in mouse brain neural cells.

Lin, Ho-Chen; Huang, Chin-Lin; Huang, Yuh-Jeen; Hsiao, I-Lun; Yang, Chung-Wei; Chuang, Chun-Yu

Lin, Ho-Chen; Huang, Chin-Lin; Huang, Yuh-Jeen; Hsiao, I-Lun; Yang, Chung-Wei; Chuang, Chun-Yu.

Afiliação

Lin HC; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan.
Huang CL; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan.
Huang YJ; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan.
Hsiao IL; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan.
Yang CW; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan.
Chuang CY; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan. Electronic address: cychuang@mx.nthu.edu.tw.

Toxicol In Vitro ; 34: 289-299, 2016 Aug.

Article em En | MEDLINE | ID: mdl-27131904

Assuntos

Astrócitos/efeitos dos fármacos; Nanopartículas Metálicas/toxicidade; Microglia/efeitos dos fármacos; Neurônios/efeitos dos fármacos; Prata/toxicidade; Peptídeos beta-Amiloides/metabolismo; Precursor de Proteína beta-Amiloide/metabolismo; Animais; Astrócitos/metabolismo; Encéfalo/citologia; Linhagem Celular; Linhagem Celular Tumoral; Expressão Gênica/efeitos dos fármacos; Perfilação da Expressão Gênica; Camundongos; Microglia/metabolismo; Proteínas Quinases Ativadas por Mitógeno/metabolismo; Neurônios/metabolismo; Presenilina-1/genética; Presenilina-2/genética

Palavras-chave

Alzheimer's disease; Beta amyloid; Gene network; Neurodegenerative disease; Silver nanoparticle

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prata / Astrócitos / Microglia / Nanopartículas Metálicas / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Toxicol In Vitro Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google