Mid-luteal phase injection of subcutaneous leuprolide acetate improves live delivered pregnancy and implantation rates in younger women undergoing in vitro fertilization-embryo transfer (IVF-ET).
Clin Exp Obstet Gynecol
; 43(2): 173-4, 2016.
Article
em En
| MEDLINE
| ID: mdl-27132401
ABSTRACT
PURPOSE:
To determine if a single injection of one-mg leuprolide acetate three days after embryo transfer (ET) in younger women causes an increase in pregnancy rates, and if so, is it associated with a higher initial serum hCG level? MATERIALS ANDMETHODS:
A prospective study was initiated where women aged ≤ 35 years were offered the option of taking the leuprolide or not.RESULTS:
Though a significant difference was not found, there was a trend for higher live delivered pregnancy rates in those taking the leuprolide supplement (47.8%) vs. those not taking it (38.6%). There was no difference in the first serum beta hCG level.CONCLUSIONS:
The trends is interesting enough to continue with a higher powered study.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fertilização in vitro
/
Leuprolida
/
Transferência Embrionária
/
Fármacos para a Fertilidade Feminina
/
Infertilidade Feminina
Tipo de estudo:
Observational_studies
Limite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Clin Exp Obstet Gynecol
Ano de publicação:
2016
Tipo de documento:
Article