Generation of Human Liver Chimeric Mice for the Study of Human Hepatotropic Pathogens.
Methods Mol Biol
; 1438: 79-101, 2016.
Article
em En
| MEDLINE
| ID: mdl-27150085
Human liver chimeric mice have become valuable tools for the study of human hepatotropic pathogens and for the investigation of metabolism and pharmacokinetics of novel drugs. The evolution of the underlying mouse models has been rapid in the past years. The diverse fields of applications of those model systems and their technical challenges will be discussed in this chapter.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
MEDLINE
Assunto principal:
Quimeras de Transplante
/
Hepatócitos
/
Fígado
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Methods Mol Biol
Ano de publicação:
2016
Tipo de documento:
Article