Treatment of acute myeloid leukaemia with a triple cytotoxic regime: DAT.
Br J Cancer
; 36(6): 770-6, 1977 Dec.
Article
em En
| MEDLINE
| ID: mdl-271512
ABSTRACT
Twenty patients with acute myeloid leukaemia (AML) were treated with a combination of chemotherapy which included daunorubicin, cytosine arabino-side and 6-thioguanine (DAT). The complete remission rate was 85% and was achieved, in responsive cases, after an average of 2 courses of therapy. Patients remained in hospital for an average of 37.5 days during remission-induction therapy and 3.7 days per month thereafter. The median remission period was 48 weeks and median survival was 70 weeks. A disappointing feature was the high relapse rate. This feature of the results re-affirms the need for a more effective form of remission therapy.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tioguanina
/
Leucemia Mieloide Aguda
/
Daunorrubicina
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Citarabina
Tipo de estudo:
Prognostic_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Br J Cancer
Ano de publicação:
1977
Tipo de documento:
Article