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Structural analysis of human KDM5B guides histone demethylase inhibitor development.
Johansson, Catrine; Velupillai, Srikannathasan; Tumber, Anthony; Szykowska, Aleksandra; Hookway, Edward S; Nowak, Radoslaw P; Strain-Damerell, Claire; Gileadi, Carina; Philpott, Martin; Burgess-Brown, Nicola; Wu, Na; Kopec, Jola; Nuzzi, Andrea; Steuber, Holger; Egner, Ursula; Badock, Volker; Munro, Shonagh; LaThangue, Nicholas B; Westaway, Sue; Brown, Jack; Athanasou, Nick; Prinjha, Rab; Brennan, Paul E; Oppermann, Udo.
Afiliação
  • Johansson C; Structural Genomics Consortium, University of Oxford, Headington, UK.
  • Velupillai S; Botnar Research Centre, NIHR Oxford Biomedical Research Unit, University of Oxford, Oxford, UK.
  • Tumber A; Structural Genomics Consortium, University of Oxford, Headington, UK.
  • Szykowska A; Structural Genomics Consortium, University of Oxford, Headington, UK.
  • Hookway ES; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Nowak RP; Structural Genomics Consortium, University of Oxford, Headington, UK.
  • Strain-Damerell C; Botnar Research Centre, NIHR Oxford Biomedical Research Unit, University of Oxford, Oxford, UK.
  • Gileadi C; Structural Genomics Consortium, University of Oxford, Headington, UK.
  • Philpott M; Botnar Research Centre, NIHR Oxford Biomedical Research Unit, University of Oxford, Oxford, UK.
  • Burgess-Brown N; Structural Genomics Consortium, University of Oxford, Headington, UK.
  • Wu N; Structural Genomics Consortium, University of Oxford, Headington, UK.
  • Kopec J; Botnar Research Centre, NIHR Oxford Biomedical Research Unit, University of Oxford, Oxford, UK.
  • Nuzzi A; Structural Genomics Consortium, University of Oxford, Headington, UK.
  • Steuber H; Botnar Research Centre, NIHR Oxford Biomedical Research Unit, University of Oxford, Oxford, UK.
  • Egner U; Structural Genomics Consortium, University of Oxford, Headington, UK.
  • Badock V; Structural Genomics Consortium, University of Oxford, Headington, UK.
  • Munro S; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • LaThangue NB; Bayer Healthcare Pharmaceuticals, Berlin, Germany.
  • Westaway S; Bayer Healthcare Pharmaceuticals, Berlin, Germany.
  • Brown J; Bayer Healthcare Pharmaceuticals, Berlin, Germany.
  • Athanasou N; Department of Oncology, University of Oxford, Oxford, UK.
  • Prinjha R; Department of Oncology, University of Oxford, Oxford, UK.
  • Brennan PE; Epinova DPU, Immuno-Inflammation Therapy Area, GlaxoSmithKline R&D, Stevenage, UK.
  • Oppermann U; Epinova DPU, Immuno-Inflammation Therapy Area, GlaxoSmithKline R&D, Stevenage, UK.
Nat Chem Biol ; 12(7): 539-45, 2016 07.
Article em En | MEDLINE | ID: mdl-27214403
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Proteínas Nucleares / Inibidores Enzimáticos / Histona Desmetilases / Histona Desmetilases com o Domínio Jumonji / Mieloma Múltiplo / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Chem Biol Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Proteínas Nucleares / Inibidores Enzimáticos / Histona Desmetilases / Histona Desmetilases com o Domínio Jumonji / Mieloma Múltiplo / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Chem Biol Ano de publicação: 2016 Tipo de documento: Article