Formation of supramolecular assemblies and liquid crystals by purine nucleobases and cyanuric acid in water: implications for the possible origins of RNA.
Phys Chem Chem Phys
; 18(30): 20091-6, 2016 Jul 27.
Article
em En
| MEDLINE
| ID: mdl-27253677
The free nucleobases and mononucleotides of RNA do not form Watson-Crick base pairs in water, a fact that presents several challenges for the prebiotic synthesis of RNA. 2,6-Diaminopurine and adenosine-5'-monophosphate (AMP) are shown to form supramolecular assemblies with cyanuric acid in water. These assemblies and their propensity to form liquid crystals suggest a possible means by which non-covalent structures might have originally selected the shape of the Watson-Crick base pairs.
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01-internacional
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MEDLINE
Idioma:
En
Revista:
Phys Chem Chem Phys
Ano de publicação:
2016
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Article