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Harnessing Fluorine-Sulfur Contacts and Multipolar Interactions for the Design of p53 Mutant Y220C Rescue Drugs.
Bauer, Matthias R; Jones, Rhiannon N; Baud, Matthias G J; Wilcken, Rainer; Boeckler, Frank M; Fersht, Alan R; Joerger, Andreas C; Spencer, John.
Afiliação
  • Bauer MR; MRC Laboratory of Molecular Biology , Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, United Kingdom.
  • Jones RN; Department of Chemistry, School of Life Sciences, University of Sussex , Falmer, Brighton, East Sussex BN1 9QJ, United Kingdom.
  • Baud MG; MRC Laboratory of Molecular Biology , Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, United Kingdom.
  • Wilcken R; MRC Laboratory of Molecular Biology , Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, United Kingdom.
  • Boeckler FM; Molecular Design and Pharmaceutical Biophysics, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen , Auf der Morgenstelle 8, 72076 Tübingen, Germany.
  • Fersht AR; MRC Laboratory of Molecular Biology , Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, United Kingdom.
  • Joerger AC; MRC Laboratory of Molecular Biology , Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, United Kingdom.
  • Spencer J; Department of Chemistry, School of Life Sciences, University of Sussex , Falmer, Brighton, East Sussex BN1 9QJ, United Kingdom.
ACS Chem Biol ; 11(8): 2265-74, 2016 08 19.
Article em En | MEDLINE | ID: mdl-27267810
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Enxofre / Desenho de Fármacos / Proteína Supressora de Tumor p53 / Flúor / Mutação Idioma: En Revista: ACS Chem Biol Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Enxofre / Desenho de Fármacos / Proteína Supressora de Tumor p53 / Flúor / Mutação Idioma: En Revista: ACS Chem Biol Ano de publicação: 2016 Tipo de documento: Article