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Efficacy and Safety of 'Fixed Dose' versus 'Loose' Drug Regimens for Treatment of Pulmonary Tuberculosis in Two High TB-Burden African Countries: A Randomized Controlled Trial.
Aseffa, Abraham; Chukwu, Joseph N; Vahedi, Mahnaz; Aguwa, Emmanuel N; Bedru, Ahmed; Mebrahtu, Tesfamariam; Ezechi, Oliver C; Yimer, Getnet; Yamuah, Lawrence K; Medhin, Girmay; Connolly, Cathy; Rida, Wasima; Aderaye, Getachew; Zumla, Alimuddin I; Onyebujoh, Philip C.
Afiliação
  • Aseffa A; Armauer Hansen Research Institute (AHRI), ALERT Compound, Addis Ababa, Ethiopia.
  • Chukwu JN; German Leprosy and Tuberculosis Relief Association, Hill View, Enugu, Nigeria.
  • Vahedi M; Special Programme for Research and Training in Tropical Diseases (WHO/TDR), Avenue Appia, Geneva, Switzerland.
  • Aguwa EN; University of Nigeria Enugu Campus, Enugu, Nigeria.
  • Bedru A; Armauer Hansen Research Institute (AHRI), ALERT Compound, Addis Ababa, Ethiopia.
  • Mebrahtu T; Armauer Hansen Research Institute (AHRI), ALERT Compound, Addis Ababa, Ethiopia.
  • Ezechi OC; Division of Clinical Sciences, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
  • Yimer G; Department of Pharmacology, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
  • Yamuah LK; Armauer Hansen Research Institute (AHRI), ALERT Compound, Addis Ababa, Ethiopia.
  • Medhin G; Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
  • Connolly C; Biostatistics Unit, Medical Research Council, Durban, South Africa.
  • Rida W; Biostatistics Consultant, Arlington, Virginia, United States of America.
  • Aderaye G; Department of Internal Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
  • Zumla AI; Division of Infection and Immunity, Centre for Clinical Microbiology, University College London, and NIHR Biomedical Research Centre, UCL Hospitals NHS Foundation Trust, London, United Kingdom.
  • Onyebujoh PC; World Health Organization, Inter-country Support Team for East and Southern Africa, Harare, Zimbabwe.
PLoS One ; 11(6): e0157434, 2016.
Article em En | MEDLINE | ID: mdl-27322164

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 3_ND Base de dados: MEDLINE Assunto principal: Tuberculose Pulmonar / Relação Dose-Resposta a Droga Tipo de estudo: Clinical_trials / Guideline / Observational_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Africa Idioma: En Revista: PLoS One Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 3_ND Base de dados: MEDLINE Assunto principal: Tuberculose Pulmonar / Relação Dose-Resposta a Droga Tipo de estudo: Clinical_trials / Guideline / Observational_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Africa Idioma: En Revista: PLoS One Ano de publicação: 2016 Tipo de documento: Article