Ursodeoxycholic acid inhibits TNF&#945;-induced IL-8 release from monocytes.

O'Dwyer, Aoife M; Lajczak, Natalia K; Keyes, Jennifer A; Ward, Joseph B; Greene, Catherine M; Keely, Stephen J

Ursodeoxycholic acid inhibits TNFα-induced IL-8 release from monocytes.

O'Dwyer, Aoife M; Lajczak, Natalia K; Keyes, Jennifer A; Ward, Joseph B; Greene, Catherine M; Keely, Stephen J.

Afiliação

O'Dwyer AM; Department of Molecular Medicine, Royal College of Surgeons in Ireland, Education & Research Centre, Beaumont Hospital, Dublin, Ireland; and.
Lajczak NK; Department of Molecular Medicine, Royal College of Surgeons in Ireland, Education & Research Centre, Beaumont Hospital, Dublin, Ireland; and.
Keyes JA; Department of Molecular Medicine, Royal College of Surgeons in Ireland, Education & Research Centre, Beaumont Hospital, Dublin, Ireland; and.
Ward JB; Department of Molecular Medicine, Royal College of Surgeons in Ireland, Education & Research Centre, Beaumont Hospital, Dublin, Ireland; and.
Greene CM; Department of Medicine, Royal College of Surgeons in Ireland, Education & Research Centre, Beaumont Hospital, Dublin, Ireland.
Keely SJ; Department of Molecular Medicine, Royal College of Surgeons in Ireland, Education & Research Centre, Beaumont Hospital, Dublin, Ireland; and skeely@rcsi.ie.

Am J Physiol Gastrointest Liver Physiol ; 311(2): G334-41, 2016 08 01.

Article em En | MEDLINE | ID: mdl-27340129

Assuntos

Imunossupressores/farmacologia; Interleucina-8/metabolismo; Monócitos/efeitos dos fármacos; Fator de Necrose Tumoral alfa/farmacologia; Ácido Ursodesoxicólico/farmacologia; Regulação da Expressão Gênica; Humanos; Imunidade nas Mucosas/efeitos dos fármacos; Interleucina-8/genética; Interleucina-8/imunologia; Lipopolissacarídeos/farmacologia; Monócitos/imunologia; Monócitos/metabolismo; NF-kappa B/metabolismo; Fosforilação; Transdução de Sinais/efeitos dos fármacos; Fator 2 Associado a Receptor de TNF/metabolismo; Células U937

Palavras-chave

colitis; cytokine; innate immunity; monocyte; ursodeoxycholic acid

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Ursodesoxicólico / Monócitos / Interleucina-8 / Fator de Necrose Tumoral alfa / Imunossupressores Limite: Humans Idioma: En Revista: Am J Physiol Gastrointest Liver Physiol Ano de publicação: 2016 Tipo de documento: Article

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