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The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding.
Woodford, Mark R; Dunn, Diana M; Blanden, Adam R; Capriotti, Dante; Loiselle, David; Prodromou, Chrisostomos; Panaretou, Barry; Hughes, Philip F; Smith, Aaron; Ackerman, Wendi; Haystead, Timothy A; Loh, Stewart N; Bourboulia, Dimitra; Schmidt, Laura S; Marston Linehan, W; Bratslavsky, Gennady; Mollapour, Mehdi.
Afiliação
  • Woodford MR; Department of Urology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA.
  • Dunn DM; Cancer Research Institute, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA.
  • Blanden AR; Department of Urology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA.
  • Capriotti D; Cancer Research Institute, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA.
  • Loiselle D; Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA.
  • Prodromou C; Cancer Research Institute, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA.
  • Panaretou B; Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA.
  • Hughes PF; Department of Urology, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA.
  • Smith A; Cancer Research Institute, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA.
  • Ackerman W; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.
  • Haystead TA; Genome Damage and Stability Centre, University of Sussex, Brighton BN1 9RQ, UK.
  • Loh SN; Institute of Pharmaceutical Science, King's College London, London SE1 9NH, UK.
  • Bourboulia D; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.
  • Schmidt LS; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.
  • Marston Linehan W; Health Sciences Library, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA.
  • Bratslavsky G; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.
  • Mollapour M; Cancer Research Institute, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA.
Nat Commun ; 7: 12037, 2016 06 29.
Article em En | MEDLINE | ID: mdl-27353360
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Proteínas Proto-Oncogênicas / Proteínas de Choque Térmico HSP90 / Proteínas Supressoras de Tumor / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Proteínas Proto-Oncogênicas / Proteínas de Choque Térmico HSP90 / Proteínas Supressoras de Tumor / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Ano de publicação: 2016 Tipo de documento: Article