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Curcumin ameliorates neuropathic pain by down-regulating spinal IL-1ß via suppressing astroglial NALP1 inflammasome and JAK2-STAT3 signalling.
Liu, Shenbin; Li, Qian; Zhang, Meng-Ting; Mao-Ying, Qi-Liang; Hu, Lang-Yue; Wu, Gen-Cheng; Mi, Wen-Li; Wang, Yan-Qing.
Afiliação
  • Liu S; Department of Integrative Medicine and Neurobiology, The Academy of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200032, China.
  • Li Q; Department of Integrative Medicine and Neurobiology, The Academy of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200032, China.
  • Zhang MT; Department of Integrative Medicine and Neurobiology, The Academy of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200032, China.
  • Mao-Ying QL; Department of Integrative Medicine and Neurobiology, The Academy of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200032, China.
  • Hu LY; Department of Integrative Medicine and Neurobiology, The Academy of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200032, China.
  • Wu GC; Department of Integrative Medicine and Neurobiology, The Academy of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200032, China.
  • Mi WL; Department of Integrative Medicine and Neurobiology, The Academy of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200032, China.
  • Wang YQ; Department of Integrative Medicine and Neurobiology, The Academy of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200032, China.
Sci Rep ; 6: 28956, 2016 07 06.
Article em En | MEDLINE | ID: mdl-27381056
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação para Baixo / Curcumina / Proteínas Adaptadoras de Transdução de Sinal / Fator de Transcrição STAT3 / Proteínas Reguladoras de Apoptose / Janus Quinase 2 / Interleucina-1beta / Neuralgia Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação para Baixo / Curcumina / Proteínas Adaptadoras de Transdução de Sinal / Fator de Transcrição STAT3 / Proteínas Reguladoras de Apoptose / Janus Quinase 2 / Interleucina-1beta / Neuralgia Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article