Long-lasting extreme anemia during the therapy of acute lymphoblastic leukemia in a Jehovah's Witness patient.
Transfusion
; 56(10): 2438-2442, 2016 Oct.
Article
em En
| MEDLINE
| ID: mdl-27385671
ABSTRACT
BACKGROUND:
The treatment of patients with acute leukemia, who due to their religious beliefs refuse to accept blood transfusion, is a great challenge for hematologists. CASE REPORT We present a case of acute pre-T-lymphoblastic leukemia in a Jehovah's Witness who did not accept blood transfusion during chemotherapy. Standard induction and consolidation chemotherapy was used (according to the PALG ALL-6 regiment).RESULTS:
During consolidation cycles, darbepoietin alfa, intravenous iron, and total parenteral nutrition was administered. Extreme (Hb < 5 g/dL), long-lasting (41 days) anemia was observed with the lowest Hb concentration amounting to 1.3 g/dL (lasting 7 days).CONCLUSION:
We believe this to be the lowest Hb value observed, particularly one that persisted for such a long period of time and resulted in the patient surviving without consequences. The patient remains in complete remission for more than 2 years after diagnosis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Testemunhas de Jeová
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
/
Anemia
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Transfusion
Ano de publicação:
2016
Tipo de documento:
Article