High Glucose-Induced PC12 Cell Death by Increasing Glutamate Production and Decreasing Methyl Group Metabolism.

Chen, Minjiang; Zheng, Hong; Wei, Tingting; Wang, Dan; Xia, Huanhuan; Zhao, Liangcai; Ji, Jiansong; Gao, Hongchang

Chen, Minjiang; Zheng, Hong; Wei, Tingting; Wang, Dan; Xia, Huanhuan; Zhao, Liangcai; Ji, Jiansong; Gao, Hongchang.

Afiliação

Chen M; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China; Lishui Central Hospital, The Fifth Affiliated Hospital, Wenzhou Medical University, Lishui 323000, China.
Zheng H; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Wei T; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Wang D; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Xia H; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Zhao L; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Ji J; Lishui Central Hospital, The Fifth Affiliated Hospital, Wenzhou Medical University, Lishui 323000, China.
Gao H; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.

Biomed Res Int ; 2016: 4125731, 2016.

Article em En | MEDLINE | ID: mdl-27413747

Assuntos

Aminoácidos/metabolismo; Apoptose/fisiologia; Glucose/farmacocinética; Ácido Glutâmico/biossíntese; Hidrocarbonetos/metabolismo; Metaboloma/fisiologia; Animais; Glucose/administração & dosagem; Metaboloma/efeitos dos fármacos; Células PC12; Ratos

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Apoptose / Ácido Glutâmico / Metaboloma / Aminoácidos / Glucose / Hidrocarbonetos Limite: Animals Idioma: En Revista: Biomed Res Int Ano de publicação: 2016 Tipo de documento: Article

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