Empowering Regulatory T Cells in Autoimmunity.
Trends Mol Med
; 22(9): 784-797, 2016 09.
Article
em En
| MEDLINE
| ID: mdl-27461103
ABSTRACT
Regulatory T cells (Tregs) are capable of dampening immune-mediated inflammation and avert the destructive effects of uncontrolled inflammation. Distinct molecules and pathways, including various transcription factors, phosphatases, and kinases, impact the ability of Tregs to function as negative regulators of the immune response, and are presumably amenable to therapeutic manipulation. Here, we discuss recently identified molecular networks and the therapeutic potential for treating autoimmune diseases.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Autoimunes
/
Autoimunidade
/
Linfócitos T Reguladores
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Trends Mol Med
Ano de publicação:
2016
Tipo de documento:
Article