Antibiotics Prophylaxis for Operative Hysteroscopy.
Reprod Sci
; 24(4): 534-538, 2017 04.
Article
em En
| MEDLINE
| ID: mdl-27470152
ABSTRACT
OBJECTIVE:
To evaluate the incidence of infectious complications and effect of prophylactic antibiotic administration during operative hysteroscopic procedures.METHODS:
A multicentric randomized controlled trial was conducted between January 2012 and December 2013. Women (n = 180) affected by endometrial hyperplasia, myomas, or endometrial polyps undergoing operative hysteroscopy were randomized to receive cefazolin 2 g intravenously 30 minutes prior to the procedure (n = 91) and no treatment (n = 89).RESULTS:
No statistical difference in terms of postoperative fever (2.4% vs 2.3%, P = .99), endometritis (0% vs 0%), pain (6.0% vs 10.4%, P = .40), cervicitis-vaginitis (0% vs 0%), pelvic abscess (0% vs 0%), pelvic inflammatory disease (0% vs 0%), and bleeding (0% vs 0%) was noticed. No statistical difference in terms of side effects attributable to antibiotic prophylaxis such as allergy (0% vs 4.8%, P = .12), nausea (10.7% vs 17.4%, P = .27), vomiting (3.6% vs 4.6%, P = .99), diarrhea (4.8% vs 5.4%, P = .99), cephalea (9.5% vs 3.5%, P = .13), dizziness (4.8% vs 2.3%, P = .44), and meteorism (5.4% vs 3.4%, P = .99) was noticed.CONCLUSION:
The results of the current study support the recommendation not to prescribe routine antibiotic prophylaxis prior to operative hysteroscopy.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
MEDLINE
Assunto principal:
Pólipos
/
Neoplasias Uterinas
/
Histeroscopia
/
Antibioticoprofilaxia
/
Hiperplasia Endometrial
/
Leiomioma
Tipo de estudo:
Clinical_trials
/
Guideline
Limite:
Adult
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Reprod Sci
Ano de publicação:
2017
Tipo de documento:
Article