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A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition.
Li, Dalin; Achkar, Jean-Paul; Haritunians, Talin; Jacobs, Jonathan P; Hui, Ken Y; D'Amato, Mauro; Brand, Stephan; Radford-Smith, Graham; Halfvarson, Jonas; Niess, Jan-Hendrik; Kugathasan, Subra; Büning, Carsten; Schumm, L Philip; Klei, Lambertus; Ananthakrishnan, Ashwin; Aumais, Guy; Baidoo, Leonard; Dubinsky, Marla; Fiocchi, Claudio; Glas, Jürgen; Milgrom, Raquel; Proctor, Deborah D; Regueiro, Miguel; Simms, Lisa A; Stempak, Joanne M; Targan, Stephan R; Törkvist, Leif; Sharma, Yashoda; Devlin, Bernie; Borneman, James; Hakonarson, Hakon; Xavier, Ramnik J; Daly, Mark; Brant, Steven R; Rioux, John D; Silverberg, Mark S; Cho, Judy H; Braun, Jonathan; McGovern, Dermot P B; Duerr, Richard H.
Afiliação
  • Li D; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California.
  • Achkar JP; Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, Ohio.
  • Haritunians T; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California.
  • Jacobs JP; Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.
  • Hui KY; Division of Gastroenterology, Department of Medicine, Yale University, New Haven, Connecticut.
  • D'Amato M; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden; Biocruces Health Research Institute, Barakaldo, Bizkaia, Spain.
  • Brand S; Department of Medicine II, University Hospital Munich-Grosshadern, Munich, Germany.
  • Radford-Smith G; Inflammatory Bowel Diseases, Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia; Department of Gastroenterology, Royal Brisbane and Women's Hospital, Brisbane, Australia; School of Medicine, University of Queensland, Brisbane, Australia.
  • Halfvarson J; Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Orebro, Sweden.
  • Niess JH; Department of Internal Medicine I, University of Ulm, Ulm, Germany; Division of Visceral Surgery and Medicine, Department of Gastroenterology, Inselspital Bern, Bern, Switzerland; Gastroenterology and Hepatology, University Hospital Basel, Basel, Switzerland.
  • Kugathasan S; Department of Pediatrics, Emory University School of Medicine and Children's Health Care of Atlanta, Atlanta, Georgia.
  • Büning C; Internal Medicine, Krankenhaus Waldfriede, Berlin, Germany.
  • Schumm LP; Department of Public Health Sciences, Biostatistical Laboratory, University of Chicago, Chicago, Illinois.
  • Klei L; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Ananthakrishnan A; Gastroenterology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
  • Aumais G; Université de Montréal, Montréal, Québec, Canada; Hopital Maisonneuve Rosemont, Montréal, Québec, Canada.
  • Baidoo L; Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Dubinsky M; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Fiocchi C; Pathobiology Department, Cleveland Clinic, Cleveland, Ohio.
  • Glas J; Department of Preventive Dentistry and Periodontology, Ludwig-Maximilians-University, Munich, Germany.
  • Milgrom R; Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
  • Proctor DD; Division of Gastroenterology, Department of Medicine, Yale University, New Haven, Connecticut.
  • Regueiro M; Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Simms LA; Inflammatory Bowel Diseases, Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Stempak JM; Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
  • Targan SR; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California.
  • Törkvist L; Department of Clinical Science Intervention and Technology, Karolinska Institutet, Stockholm, Sweden; Center for Digestive Disease, IBD-unit, Karolinska University Hospital, Stockholm, Sweden.
  • Sharma Y; Department of Genetic & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Devlin B; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Borneman J; Department of Plant Pathology and Microbiology, University of California, Riverside, Riverside, California.
  • Hakonarson H; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  • Xavier RJ; Gastroenterology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
  • Daly M; Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
  • Brant SR; Division of Gastroenterology and Hepatology, School of Medicine, Johns Hopkins University, Baltimore, Maryland; Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.
  • Rioux JD; Université de Montréal, Montréal, Québec, Canada; Montreal Heart Institute, Montréal, Québec, Canada.
  • Silverberg MS; Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
  • Cho JH; Department of Genetic & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Braun J; Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.
  • McGovern DP; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California.
  • Duerr RH; Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address: duerr@pitt.
Gastroenterology ; 151(4): 724-32, 2016 10.
Article em En | MEDLINE | ID: mdl-27492617
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Colite Ulcerativa / Doença de Crohn / Mutação de Sentido Incorreto / Proteínas de Transporte de Cátions / Microbioma Gastrointestinal Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Gastroenterology Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Colite Ulcerativa / Doença de Crohn / Mutação de Sentido Incorreto / Proteínas de Transporte de Cátions / Microbioma Gastrointestinal Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Gastroenterology Ano de publicação: 2016 Tipo de documento: Article