Impaired Cardiolipin Biosynthesis Prevents Hepatic Steatosis and Diet-Induced Obesity.

Cole, Laura K; Mejia, Edgard M; Vandel, Marilyne; Sparagna, Genevieve C; Claypool, Steven M; Dyck-Chan, Laura; Klein, Julianne; Hatch, Grant M

Cole, Laura K; Mejia, Edgard M; Vandel, Marilyne; Sparagna, Genevieve C; Claypool, Steven M; Dyck-Chan, Laura; Klein, Julianne; Hatch, Grant M.

Afiliação

Cole LK; Children's Hospital Research Institute of Manitoba, Department of Pharmacology & Therapeutics, Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.
Mejia EM; Children's Hospital Research Institute of Manitoba, Department of Pharmacology & Therapeutics, Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.
Vandel M; Children's Hospital Research Institute of Manitoba, Department of Pharmacology & Therapeutics, Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.
Sparagna GC; Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO.
Claypool SM; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD.
Dyck-Chan L; Children's Hospital Research Institute of Manitoba, Department of Pharmacology & Therapeutics, Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.
Klein J; Diagnostic Services of Manitoba, Winnipeg, Canada.
Hatch GM; Children's Hospital Research Institute of Manitoba, Department of Pharmacology & Therapeutics, Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada ghatch@chrim.ca.

Diabetes ; 65(11): 3289-3300, 2016 Nov.

Article em En | MEDLINE | ID: mdl-27495222

Assuntos

Cardiolipinas/biossíntese; Cardiolipinas/metabolismo; Fígado Gorduroso/metabolismo; Fígado/metabolismo; Obesidade/metabolismo; Aciltransferases; Animais; Western Blotting; Células Cultivadas; Dieta Hiperlipídica/efeitos adversos; Feminino; Hepatócitos/metabolismo; Metabolismo dos Lipídeos/fisiologia; Lipogênese/fisiologia; Fígado/patologia; Masculino; Camundongos; Camundongos Transgênicos; Mitocôndrias/metabolismo; Obesidade/etiologia; Obesidade/genética; Oxirredução; Fatores de Transcrição/deficiência; Fatores de Transcrição/metabolismo; Aumento de Peso/genética; Aumento de Peso/fisiologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cardiolipinas / Fígado Gorduroso / Fígado / Obesidade Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Diabetes Ano de publicação: 2016 Tipo de documento: Article

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