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6-Aryl-4-amino-pyrimido[4,5-b]indole 2'-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study.
Bosáková, Andrea; Perlíková, Pavla; Tichý, Michal; Pohl, Radek; Hocek, Michal.
Afiliação
  • Bosáková A; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic.
  • Perlíková P; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic.
  • Tichý M; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic.
  • Pohl R; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic.
  • Hocek M; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic; Department of Organic Chemistry, Faculty of Science, Charles University in Prague, Hlavova 8, CZ-12843 Prague
Bioorg Med Chem ; 24(19): 4528-4535, 2016 10 01.
Article em En | MEDLINE | ID: mdl-27498304

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Sondas de Oligonucleotídeos / Nucleotídeos de Desoxiadenina / Desoxirribonucleosídeos / Corantes Fluorescentes / Indóis Idioma: En Revista: Bioorg Med Chem Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Sondas de Oligonucleotídeos / Nucleotídeos de Desoxiadenina / Desoxirribonucleosídeos / Corantes Fluorescentes / Indóis Idioma: En Revista: Bioorg Med Chem Ano de publicação: 2016 Tipo de documento: Article