Proteomic identification of cyclophilin A as a potential biomarker and therapeutic target in oral submucous fibrosis.

Yuan, Yao; Hou, Xiaohui; Feng, Hui; Liu, Rui; Xu, Hao; Gong, Wang; Deng, Jing; Sun, Chongkui; Gao, Yijun; Peng, Jieying; Wu, Yingfang; Li, Jiang; Fang, Changyun; Chen, Qianming

Yuan, Yao; Hou, Xiaohui; Feng, Hui; Liu, Rui; Xu, Hao; Gong, Wang; Deng, Jing; Sun, Chongkui; Gao, Yijun; Peng, Jieying; Wu, Yingfang; Li, Jiang; Fang, Changyun; Chen, Qianming.

Afiliação

Yuan Y; State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu China, 610041.
Hou X; Laboratory of Oral Biomedical Science and Translational Medicine, School of Stomatology, Tongji University, Shanghai China, 200072.
Feng H; Xiangya Stomatological Hospital, Central South University, Changsha, China, 410008.
Liu R; State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu China, 610041.
Xu H; State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu China, 610041.
Gong W; State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu China, 610041.
Deng J; State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu China, 610041.
Sun C; State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu China, 610041.
Gao Y; Department of Stomatology, Second Xiangya Hospital, Central South University, Changsha, China, 410008.
Peng J; Center of Stomatology, Xiangya Hospital, Central South University, Changsha, China, 410008.
Wu Y; Center of Stomatology, Xiangya Hospital, Central South University, Changsha, China, 410008.
Li J; Center of Stomatology, Xiangya Hospital, Central South University, Changsha, China, 410008.
Fang C; Center of Stomatology, Xiangya Hospital, Central South University, Changsha, China, 410008.
Chen Q; State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu China, 610041.

Oncotarget ; 7(37): 60348-60365, 2016 Sep 13.

Article em En | MEDLINE | ID: mdl-27533088

Assuntos

Biomarcadores/metabolismo; Ciclofilina A/metabolismo; Fibroblastos/metabolismo; Fibrose Oral Submucosa/metabolismo; Proteômica/métodos; Apoptose/genética; Carcinoma de Células Escamosas/genética; Carcinoma de Células Escamosas/metabolismo; Linhagem Celular; Proliferação de Células/genética; Transformação Celular Neoplásica/genética; Transformação Celular Neoplásica/metabolismo; Ciclofilina A/genética; Eletroforese em Gel Bidimensional; Humanos; Neoplasias Bucais/genética; Neoplasias Bucais/metabolismo; Interferência de RNA; Espectrometria de Massas em Tandem

Palavras-chave

CypA; fibroblast; oral submucous fibrosis; proteomics

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Fibrose Oral Submucosa / Biomarcadores / Ciclofilina A / Proteômica / Fibroblastos Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Oncotarget Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google