LKB1 inhibits HPV-associated cancer progression by targeting cellular metabolism.

Zeng, Q; Chen, J; Li, Y; Werle, K D; Zhao, R-X; Quan, C-S; Wang, Y-S; Zhai, Y-X; Wang, J-W; Youssef, M; Cui, R; Liang, J; Genovese, N; Chow, L T; Li, Y-L; Xu, Z-X

Zeng, Q; Chen, J; Li, Y; Werle, K D; Zhao, R-X; Quan, C-S; Wang, Y-S; Zhai, Y-X; Wang, J-W; Youssef, M; Cui, R; Liang, J; Genovese, N; Chow, L T; Li, Y-L; Xu, Z-X.

Afiliação

Zeng Q; Key Laboratory of Pathobiology, Ministry of Education, Norman Bethune College of Medicine, Jilin University, Changchun, China.
Chen J; Division of Hematology and Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Li Y; Division of Hematology and Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Werle KD; Division of Hematology and Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Zhao RX; Division of Hematology and Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Quan CS; Division of Hematology and Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Wang YS; Key Laboratory of Pathobiology, Ministry of Education, Norman Bethune College of Medicine, Jilin University, Changchun, China.
Zhai YX; Key Laboratory of Pathobiology, Ministry of Education, Norman Bethune College of Medicine, Jilin University, Changchun, China.
Wang JW; Key Laboratory of Pathobiology, Ministry of Education, Norman Bethune College of Medicine, Jilin University, Changchun, China.
Youssef M; Key Laboratory of Pathobiology, Ministry of Education, Norman Bethune College of Medicine, Jilin University, Changchun, China.
Cui R; Division of Hematology and Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Liang J; Department of Dermatology, Boston University, School of Medicine, Boston, MA, USA.
Genovese N; Department of Systems Biology, UT MD Anderson Cancer Center, Houston, TX, USA.
Chow LT; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL, USA.
Li YL; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL, USA.
Xu ZX; Key Laboratory of Pathobiology, Ministry of Education, Norman Bethune College of Medicine, Jilin University, Changchun, China.

Oncogene ; 36(9): 1245-1255, 2017 03 02.

Article em En | MEDLINE | ID: mdl-27546620

Assuntos

Transformação Celular Neoplásica/metabolismo; Glucose/metabolismo; Glicólise/fisiologia; Infecções por Papillomavirus/metabolismo; Proteínas Serina-Treonina Quinases/metabolismo; Neoplasias do Colo do Útero/metabolismo; Neoplasias do Colo do Útero/patologia; Quinases Proteína-Quinases Ativadas por AMP; Animais; Apoptose; Biomarcadores Tumorais/genética; Biomarcadores Tumorais/metabolismo; Estudos de Casos e Controles; Proliferação de Células; Transformação Celular Neoplásica/patologia; Feminino; Seguimentos; Hexoquinase/genética; Hexoquinase/metabolismo; Papillomavirus Humano 16/fisiologia; Humanos; Camundongos; Camundongos Endogâmicos C57BL; Estadiamento de Neoplasias; Proteínas Oncogênicas Virais/genética; Proteínas Oncogênicas Virais/metabolismo; Proteínas E7 de Papillomavirus/genética; Proteínas E7 de Papillomavirus/metabolismo; Infecções por Papillomavirus/patologia; Infecções por Papillomavirus/virologia; Prognóstico; Proteínas Serina-Treonina Quinases/genética; Proteínas Repressoras/genética; Proteínas Repressoras/metabolismo; Células Tumorais Cultivadas; Neoplasias do Colo do Útero/virologia

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 2_ODS3 / 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Transformação Celular Neoplásica / Neoplasias do Colo do Útero / Proteínas Serina-Treonina Quinases / Infecções por Papillomavirus / Glucose / Glicólise Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Oncogene Ano de publicação: 2017 Tipo de documento: Article

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