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γ-Secretase inhibitor I inhibits neuroblastoma cells, with NOTCH and the proteasome among its targets.
Dorneburg, Carmen; Goß, Annika V; Fischer, Matthias; Roels, Frederik; Barth, Thomas F E; Berthold, Frank; Kappler, Roland; Oswald, Franz; Siveke, Jens T; Molenaar, Jan J; Debatin, Klaus-Michael; Beltinger, Christian.
Afiliação
  • Dorneburg C; Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
  • Goß AV; Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
  • Fischer M; Children's Hospital, Department of Pediatric Oncology and Hematology, University of Cologne, Cologne, Germany.
  • Roels F; Children's Hospital, Department of Pediatric Oncology and Hematology, University of Cologne, Cologne, Germany.
  • Barth TF; Department of Pathology, University Medical Center Ulm, Ulm, Germany.
  • Berthold F; Children's Hospital, Department of Pediatric Oncology and Hematology, University of Cologne, Cologne, Germany.
  • Kappler R; Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University, Munich, Germany.
  • Oswald F; Department of Internal Medicine I, University Medical Center Ulm, Ulm, Germany.
  • Siveke JT; Department of Internal Medicine, University Hospital Essen, Essen, Germany.
  • Molenaar JJ; Department of Oncogenomics, Academic Medical Center, Amsterdam, The Netherlands.
  • Debatin KM; Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
  • Beltinger C; Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
Oncotarget ; 7(39): 62799-62813, 2016 09 27.
Article em En | MEDLINE | ID: mdl-27588497
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Complexo de Endopeptidases do Proteassoma / Receptor Notch1 / Neuroblastoma Limite: Animals / Female / Humans Idioma: En Revista: Oncotarget Ano de publicação: 2016 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Complexo de Endopeptidases do Proteassoma / Receptor Notch1 / Neuroblastoma Limite: Animals / Female / Humans Idioma: En Revista: Oncotarget Ano de publicação: 2016 Tipo de documento: Article