Powering Tumor Metastasis with Recycled Fuel.

Hung, Mien-Chie; Yang, Riyao; Sun, Yutong

Hung, Mien-Chie; Yang, Riyao; Sun, Yutong.

Afiliação

Hung MC; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University, Taichung 404, Taiwan. Electronic address: mhung@mdanderson.org.
Yang R; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Sun Y; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Cancer Cell ; 30(3): 374-375, 2016 09 12.

Article em En | MEDLINE | ID: mdl-27622330

ABSTRACT

ABSTRACT

Receptor tyrosine kinase (RTK) recycling is of critical importance for RTK signaling and cancer, yet the process is poorly understood. In this issue, Ye et al. identify GOLM1 as a cargo adaptor that drives hepatocellular carcinoma metastasis by promoting EGFR recycling and provide insights into how this process is regulated.

Assuntos

Carcinoma Hepatocelular; Receptores Proteína Tirosina Quinases; Receptores ErbB; Humanos; Neoplasias Hepáticas; Transdução de Sinais

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Proteína Tirosina Quinases / Carcinoma Hepatocelular Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cancer Cell Ano de publicação: 2016 Tipo de documento: Article

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