Feed exposure to FB1 can aggravate pneumonic damages in pigs provoked by P. multocida.
Res Vet Sci
; 108: 38-46, 2016 Oct.
Article
em En
| MEDLINE
| ID: mdl-27663368
ABSTRACT
The possible interaction between Pasteurella multocida and the mycotoxin fumonisin B1 (FB1), recognised as one of the most often food/feed contaminant, was studied with the aim to evaluate whether and how FB1 can influence and/or complicate the development and severity of various pathological damages provoked by Pasteurella multocida in some internal organs of pigs. Heavier lung pathology was seen in pigs experimentally infected with Pasteurella multocida, when the same were exposed to 20ppm dietary levels of fumonisin B1 (FB1) as was assessed by gross pathology, pathomorphological examinations, clinical biochemistry and some immunological investigations. The most typical damages in FB1 treated pigs were the strong oedema in the lung and the slight oedema in the other internal organs and mild degenerative changes in the kidneys, whereas the typical pathomorphological findings in pigs infected with Pasteurella multocida was broncho-interstitial pneumonia. FB1 was found to aggravate pneumonic changes provoked by P. multocida in the cranial lobes of the lung and to complicate pneumonic damages with interstitial oedema in the lung. No macroscopic damages were observed in the pigs infected only with Pasteurella multocida. It can be concluded that the feed intake of FB1 in pigs may complicate or exacerbate the course of P. multocida serotype A infection.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por Pasteurella
/
Doenças dos Suínos
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Pasteurella multocida
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Fumonisinas
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Micotoxinas
Limite:
Animals
Idioma:
En
Revista:
Res Vet Sci
Ano de publicação:
2016
Tipo de documento:
Article