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Gene expression elucidates functional impact of polygenic risk for schizophrenia.
Fromer, Menachem; Roussos, Panos; Sieberts, Solveig K; Johnson, Jessica S; Kavanagh, David H; Perumal, Thanneer M; Ruderfer, Douglas M; Oh, Edwin C; Topol, Aaron; Shah, Hardik R; Klei, Lambertus L; Kramer, Robin; Pinto, Dalila; Gümüs, Zeynep H; Cicek, A Ercument; Dang, Kristen K; Browne, Andrew; Lu, Cong; Xie, Lu; Readhead, Ben; Stahl, Eli A; Xiao, Jianqiu; Parvizi, Mahsa; Hamamsy, Tymor; Fullard, John F; Wang, Ying-Chih; Mahajan, Milind C; Derry, Jonathan M J; Dudley, Joel T; Hemby, Scott E; Logsdon, Benjamin A; Talbot, Konrad; Raj, Towfique; Bennett, David A; De Jager, Philip L; Zhu, Jun; Zhang, Bin; Sullivan, Patrick F; Chess, Andrew; Purcell, Shaun M; Shinobu, Leslie A; Mangravite, Lara M; Toyoshiba, Hiroyoshi; Gur, Raquel E; Hahn, Chang-Gyu; Lewis, David A; Haroutunian, Vahram; Peters, Mette A; Lipska, Barbara K; Buxbaum, Joseph D.
Afiliação
  • Fromer M; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Roussos P; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Sieberts SK; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Johnson JS; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Kavanagh DH; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Perumal TM; Psychiatry, JJ Peters Virginia Medical Center, Bronx, New York, USA.
  • Ruderfer DM; Systems Biology, Sage Bionetworks, Seattle, Washington, USA.
  • Oh EC; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Topol A; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Shah HR; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Klei LL; Systems Biology, Sage Bionetworks, Seattle, Washington, USA.
  • Kramer R; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Pinto D; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Gümüs ZH; Center for Human Disease Modeling, Duke University, Durham, North Carolina, USA.
  • Cicek AE; Department of Neurology, Duke University, Durham, North Carolina, USA.
  • Dang KK; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Browne A; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Lu C; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Xie L; Human Brain Collection Core, National Institutes of Health, NIMH, Bethesda, Maryland, USA.
  • Readhead B; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Stahl EA; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Xiao J; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Parvizi M; Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Hamamsy T; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Fullard JF; Department of Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA.
  • Wang YC; Systems Biology, Sage Bionetworks, Seattle, Washington, USA.
  • Mahajan MC; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Derry JM; Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Dudley JT; Department of Statistics, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA.
  • Hemby SE; Department of Statistics, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA.
  • Logsdon BA; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Talbot K; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Raj T; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Bennett DA; Center for Human Disease Modeling, Duke University, Durham, North Carolina, USA.
  • De Jager PL; Center for Human Disease Modeling, Duke University, Durham, North Carolina, USA.
  • Zhu J; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Zhang B; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Sullivan PF; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Chess A; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Purcell SM; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Shinobu LA; Systems Biology, Sage Bionetworks, Seattle, Washington, USA.
  • Mangravite LM; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Toyoshiba H; Department of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy, High Point University, High Point, North Carolina, USA.
  • Gur RE; Systems Biology, Sage Bionetworks, Seattle, Washington, USA.
  • Hahn CG; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California, USA.
  • Lewis DA; Institute for Genomics and Multiscale Biology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Haroutunian V; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Peters MA; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Lipska BK; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
  • Buxbaum JD; The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Nat Neurosci ; 19(11): 1442-1453, 2016 11.
Article em En | MEDLINE | ID: mdl-27668389
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esquizofrenia / Regulação da Expressão Gênica / Predisposição Genética para Doença / Herança Multifatorial Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Nat Neurosci Ano de publicação: 2016 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esquizofrenia / Regulação da Expressão Gênica / Predisposição Genética para Doença / Herança Multifatorial Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Nat Neurosci Ano de publicação: 2016 Tipo de documento: Article