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Effect of Itraconazole and Rifampin on the Pharmacokinetics of Olaparib in Patients With Advanced Solid Tumors: Results of Two Phase I Open-label Studies.
Dirix, Luc; Swaisland, Helen; Verheul, Henk M W; Rottey, Sylvie; Leunen, Karin; Jerusalem, Guy; Rolfo, Christian; Nielsen, Dorte; Molife, L Rhoda; Kristeleit, Rebecca; Vos-Geelen, Judith de; Mau-Sørensen, Morten; Soetekouw, Patricia; van Herpen, Carla; Fielding, Anitra; So, Karen; Bannister, Wendy; Plummer, Ruth.
Afiliação
  • Dirix L; Medical Oncology, Sint-Augustinus-University of Antwerp, Antwerp, Belgium. Electronic address: luc.dirix@telenet.be.
  • Swaisland H; AstraZeneca, Macclesfield, United Kingdom.
  • Verheul HM; Department of Medical Oncology, VU Medisch Centrum, Amsterdam, the Netherlands.
  • Rottey S; Department of Medical Oncology, Ghent University Hospital and Heymans Institute of Pharmacology, Ghent, Belgium.
  • Leunen K; Universitair Ziekenhuizen Leuven, Leuven, Belgium.
  • Jerusalem G; CHU Sart-Tilman and Liege University, Liege, Belgium.
  • Rolfo C; Oncology Department, Universitair Ziekenhuis Antwerpen, Antwerp, Belgium.
  • Nielsen D; Department of Oncology, Herlev and Gentofte Hospital, Herlev, Denmark.
  • Molife LR; The Royal Marsden and Institute of Cancer Research, Sutton, United Kingdom.
  • Kristeleit R; University College London Cancer Institute, London, United Kingdom.
  • Vos-Geelen J; Division of Medical Oncology, Maastricht University Medical Center, Maastricht, the Netherlands.
  • Mau-Sørensen M; Department of Oncology, University Hospital, Rigshospitalet, Copenhagen, Denmark.
  • Soetekouw P; Division of Medical Oncology, Maastricht University Medical Center, Maastricht, the Netherlands.
  • van Herpen C; Radboud University Medical Center, Nijmegen, the Netherlands.
  • Fielding A; AstraZeneca, Macclesfield, United Kingdom.
  • So K; AstraZeneca, Cambridge, United Kingdom.
  • Bannister W; PHASTAR, London, United Kingdom.
  • Plummer R; Northern Centre for Cancer Care, Newcastle upon Tyne, United Kingdom.
Clin Ther ; 38(10): 2286-2299, 2016 Oct.
Article em En | MEDLINE | ID: mdl-27745744
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ftalazinas / Piperazinas / Rifampina / Itraconazol / Neoplasias Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Ther Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ftalazinas / Piperazinas / Rifampina / Itraconazol / Neoplasias Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Ther Ano de publicação: 2016 Tipo de documento: Article