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Optimization of the Ussing chamber setup with excised rat intestinal segments for dissolution/permeation experiments of poorly soluble drugs.
Forner, Kristin; Roos, Carl; Dahlgren, David; Kesisoglou, Filippos; Konerding, Moritz A; Mazur, Johanna; Lennernäs, Hans; Langguth, Peter.
Afiliação
  • Forner K; a Department of Pharmaceutical Technology and Biopharmaceutics , Johannes Gutenberg University , Mainz , Germany.
  • Roos C; b Department of Pharmacy , Uppsala University , Uppsala , Sweden.
  • Dahlgren D; b Department of Pharmacy , Uppsala University , Uppsala , Sweden.
  • Kesisoglou F; c Department of Biopharmaceutics, Pharmaceutical Sciences and Clinical Supply , Merck & Co. Inc ., Kenilworth , NJ , USA.
  • Konerding MA; d Institute of Clinical and Functional Anatomy , University Medical Center Johannes Gutenberg University , Mainz , Germany.
  • Mazur J; e Institute of Medical Biostatistics, Epidemiology and Informatics , University Medical Center Johannes Gutenberg University , Mainz , Germany.
  • Lennernäs H; b Department of Pharmacy , Uppsala University , Uppsala , Sweden.
  • Langguth P; a Department of Pharmaceutical Technology and Biopharmaceutics , Johannes Gutenberg University , Mainz , Germany.
Drug Dev Ind Pharm ; 43(2): 338-346, 2017 Feb.
Article em En | MEDLINE | ID: mdl-27762631

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Solubilidade / Ácidos e Sais Biliares / Permeabilidade da Membrana Celular / Células CACO-2 / Intestinos / Jejuno Limite: Animals / Humans Idioma: En Revista: Drug Dev Ind Pharm Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Solubilidade / Ácidos e Sais Biliares / Permeabilidade da Membrana Celular / Células CACO-2 / Intestinos / Jejuno Limite: Animals / Humans Idioma: En Revista: Drug Dev Ind Pharm Ano de publicação: 2017 Tipo de documento: Article