Ultradian glucocorticoid exposure directs gene-dependent and tissue-specific mRNA expression patterns in vivo.

George, Charlotte L; Birnie, Matthew T; Flynn, Benjamin P; Kershaw, Yvonne M; Lightman, Stafford L; Conway-Campbell, Becky L

Ultradian glucocorticoid exposure directs gene-dependent and tissue-specific mRNA expression patterns in vivo.

George, Charlotte L; Birnie, Matthew T; Flynn, Benjamin P; Kershaw, Yvonne M; Lightman, Stafford L; Conway-Campbell, Becky L.

Afiliação

George CL; Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, School of Clinical Sciences, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol, BS1 3NY, UK; CGAT, MRC Weatherall Institute of Molecular Medicine Centre for Computational Biology, University of Oxford,
Birnie MT; Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, School of Clinical Sciences, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol, BS1 3NY, UK. Electronic address: Matthew.Birnie@bristol.ac.uk.
Flynn BP; Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, School of Clinical Sciences, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol, BS1 3NY, UK. Electronic address: Ben.Flynn@bristol.ac.uk.
Kershaw YM; Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, School of Clinical Sciences, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol, BS1 3NY, UK. Electronic address: Y.Kershaw@bristol.ac.uk.
Lightman SL; Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, School of Clinical Sciences, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol, BS1 3NY, UK. Electronic address: Stafford.Lightman@bristol.ac.uk.
Conway-Campbell BL; Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, School of Clinical Sciences, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol, BS1 3NY, UK. Electronic address: B.Conway-Campbell@bristol.ac.uk.

Mol Cell Endocrinol ; 439: 46-53, 2017 01 05.

Article em En | MEDLINE | ID: mdl-27769714

Assuntos

Regulação da Expressão Gênica/efeitos dos fármacos; Glucocorticoides/farmacologia; Especificidade de Órgãos/genética; Ritmo Ultradiano/genética; Animais; Corticosterona/farmacologia; Regulação para Baixo/efeitos dos fármacos; Regulação para Baixo/genética; Proteínas Imediatamente Precoces/genética; Proteínas Imediatamente Precoces/metabolismo; Masculino; Especificidade de Órgãos/efeitos dos fármacos; Hipófise/efeitos dos fármacos; Hipófise/metabolismo; Córtex Pré-Frontal/efeitos dos fármacos; Córtex Pré-Frontal/metabolismo; Pró-Opiomelanocortina/genética; Pró-Opiomelanocortina/metabolismo; Proteínas Serina-Treonina Quinases/genética; Proteínas Serina-Treonina Quinases/metabolismo; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Ratos Sprague-Dawley; Receptores de Glucocorticoides/metabolismo; Ritmo Ultradiano/efeitos dos fármacos

Palavras-chave

GR; Glucocorticoids; Pituitary; Prefrontal cortex; Transcription; Ultradian rhythm

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Especificidade de Órgãos / Regulação da Expressão Gênica / Ritmo Ultradiano / Glucocorticoides Limite: Animals Idioma: En Revista: Mol Cell Endocrinol Ano de publicação: 2017 Tipo de documento: Article

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