Characterization of Autoantigens Targeted by Anti-Citrullinated Protein Antibodies In Vivo: Prominent Role for Epitopes Derived from Histone 4 Proteins.

Meng, Xiaobo; Ezzati, Peyman; Smolik, Irene; Bernstein, Charles N; Hitchon, Carol Ann; El-Gabalawy, Hani S

Meng, Xiaobo; Ezzati, Peyman; Smolik, Irene; Bernstein, Charles N; Hitchon, Carol Ann; El-Gabalawy, Hani S.

Afiliação

Meng X; Arthritis Centre, Department of Internal Medicine, University of Manitoba, RR149, 800 Sherbrook St. Winnipeg, MB, R3A 1M4, Canada.
Ezzati P; Manitoba Centre for Proteomics and Systems Biology, University of Manitoba, 799 JBRC, 715 McDermot Ave, Winnipeg, MB, R3E 3P4, Canada.
Smolik I; Manitoba Centre for Proteomics and Systems Biology, University of Manitoba, 799 JBRC, 715 McDermot Ave, Winnipeg, MB, R3E 3P4, Canada.
Bernstein CN; Arthritis Centre, Department of Internal Medicine, University of Manitoba, RR149, 800 Sherbrook St. Winnipeg, MB, R3A 1M4, Canada.
Hitchon CA; Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
El-Gabalawy HS; Arthritis Centre, Department of Internal Medicine, University of Manitoba, RR149, 800 Sherbrook St. Winnipeg, MB, R3A 1M4, Canada.

PLoS One ; 11(10): e0165501, 2016.

Article em En | MEDLINE | ID: mdl-27788229

Assuntos

Autoanticorpos/imunologia; Autoantígenos/imunologia; Citrulina/metabolismo; Epitopos/imunologia; Histonas/imunologia; Histonas/metabolismo; Sequência de Aminoácidos; Artrite Reumatoide/sangue; Artrite Reumatoide/imunologia; Autoanticorpos/sangue; Autoanticorpos/química; Humanos; Peptídeos Cíclicos/imunologia; Líquido Sinovial/imunologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoanticorpos / Autoantígenos / Histonas / Citrulina / Epitopos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: PLoS One Ano de publicação: 2016 Tipo de documento: Article

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