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Lead discovery for mammalian elongation of long chain fatty acids family 6 using a combination of high-throughput fluorescent-based assay and RapidFire mass spectrometry assay.
Takamiya, Mari; Sakurai, Masaaki; Teranishi, Fumie; Ikeda, Tomoko; Kamiyama, Tsutomu; Asai, Akira.
Afiliação
  • Takamiya M; Centre for Drug Discovery, Graduate School of Pharmaceutical Science, University of Shizuoka, Suruga-ku, Shizuoka, Shizuoka, Japan; Discovery Technology Laboratories, Sohyaku, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Kawagishi, Toda-shi, Saitama, Japan.
  • Sakurai M; Advanced Drug Research Laboratories, Sohyaku, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Kawagishi, Toda-shi, Saitama, Japan.
  • Teranishi F; Advanced Drug Research Laboratories, Sohyaku, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Kawagishi, Toda-shi, Saitama, Japan.
  • Ikeda T; Advanced Drug Research Laboratories, Sohyaku, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Kawagishi, Toda-shi, Saitama, Japan.
  • Kamiyama T; Discovery Technology Laboratories, Sohyaku, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Kawagishi, Toda-shi, Saitama, Japan.
  • Asai A; Centre for Drug Discovery, Graduate School of Pharmaceutical Science, University of Shizuoka, Suruga-ku, Shizuoka, Shizuoka, Japan. Electronic address: aasai@u-shizuoka-ken.ac.jp.
Biochem Biophys Res Commun ; 480(4): 721-726, 2016 Nov 25.
Article em En | MEDLINE | ID: mdl-27793673
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetiltransferases / Espectrometria de Fluorescência / Espectrometria de Massas / Preparações Farmacêuticas / Ensaios de Triagem em Larga Escala Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2016 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetiltransferases / Espectrometria de Fluorescência / Espectrometria de Massas / Preparações Farmacêuticas / Ensaios de Triagem em Larga Escala Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2016 Tipo de documento: Article