Effects of Alzheimer's Disease-Associated Risk Loci on Amyloid-ß Accumulation in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients.

Laiterä, Tiina; Paananen, Jussi; Helisalmi, Seppo; Sarajärvi, Timo; Huovinen, Joel; Laitinen, Marjo; Rauramaa, Tuomas; Alafuzoff, Irina; Remes, Anne M; Soininen, Hilkka; Haapasalo, Annakaisa; Jääskeläinen, Juha E; Leinonen, Ville; Hiltunen, Mikko

Laiterä, Tiina; Paananen, Jussi; Helisalmi, Seppo; Sarajärvi, Timo; Huovinen, Joel; Laitinen, Marjo; Rauramaa, Tuomas; Alafuzoff, Irina; Remes, Anne M; Soininen, Hilkka; Haapasalo, Annakaisa; Jääskeläinen, Juha E; Leinonen, Ville; Hiltunen, Mikko.

Afiliação

Laiterä T; Institute of Clinical Medicine - Neurology, University of Eastern Finland and Department of Neurology, Kuopio University Hospital, Kuopio, Finland.
Paananen J; Institute of Clinical Medicine - Neurosurgery, University of Eastern Finland and Neurosurgery of NeuroCenter, Kuopio University Hospital, Kuopio, Finland.
Helisalmi S; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
Sarajärvi T; Institute of Clinical Medicine - Neurology, University of Eastern Finland and Department of Neurology, Kuopio University Hospital, Kuopio, Finland.
Huovinen J; Institute of Clinical Medicine - Neurology, University of Eastern Finland and Department of Neurology, Kuopio University Hospital, Kuopio, Finland.
Laitinen M; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
Rauramaa T; Institute of Clinical Medicine - Neurosurgery, University of Eastern Finland and Neurosurgery of NeuroCenter, Kuopio University Hospital, Kuopio, Finland.
Alafuzoff I; Institute of Clinical Medicine - Neurology, University of Eastern Finland and Department of Neurology, Kuopio University Hospital, Kuopio, Finland.
Remes AM; Institute of Clinical Medicine - Pathology, University of Eastern Finland and Department of Pathology, Kuopio University Hospital, Kuopio, Finland.
Soininen H; Department of Pathology, Kuopio University Hospital, Kuopio, Finland.
Haapasalo A; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Jääskeläinen JE; Institute of Clinical Medicine - Neurology, University of Eastern Finland and Department of Neurology, Kuopio University Hospital, Kuopio, Finland.
Leinonen V; Institute of Clinical Medicine - Neurology, University of Eastern Finland and Department of Neurology, Kuopio University Hospital, Kuopio, Finland.
Hiltunen M; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.

J Alzheimers Dis ; 55(3): 995-1003, 2017.

Article em En | MEDLINE | ID: mdl-27802227

Assuntos

Doença de Alzheimer/genética; Doença de Alzheimer/patologia; Peptídeos beta-Amiloides/metabolismo; Hidrocefalia de Pressão Normal/genética; Hidrocefalia de Pressão Normal/patologia; Neocórtex/metabolismo; Idoso; Idoso de 80 Anos ou mais; Secretases da Proteína Precursora do Amiloide/metabolismo; Apolipoproteína E4/genética; Estudos de Coortes; Feminino; Estudo de Associação Genômica Ampla; Humanos; Masculino; Neocórtex/patologia; Polimorfismo de Nucleotídeo Único/genética

Palavras-chave

Alzheimer's disease; amyloid-ß; apolipoprotein E; genome wide association studies; idiopathic normal pressure hydrocephalus

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos beta-Amiloides / Neocórtex / Doença de Alzheimer / Hidrocefalia de Pressão Normal Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: J Alzheimers Dis Ano de publicação: 2017 Tipo de documento: Article

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