Efficacy and safety of Everolimus in children with TSC - associated epilepsy - Pilot data from an open single-center prospective study.

Samueli, Sharon; Abraham, Klaus; Dressler, Anastasia; Gröppel, Gudrun; Mühlebner-Fahrngruber, Angelika; Scholl, Theresa; Kasprian, Gregor; Laccone, Franco; Feucht, Martha

Samueli, Sharon; Abraham, Klaus; Dressler, Anastasia; Gröppel, Gudrun; Mühlebner-Fahrngruber, Angelika; Scholl, Theresa; Kasprian, Gregor; Laccone, Franco; Feucht, Martha.

Afiliação

Samueli S; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
Abraham K; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
Dressler A; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
Gröppel G; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
Mühlebner-Fahrngruber A; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
Scholl T; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
Kasprian G; Department of Biomedical Imaging and Image Guided Therapy, Medical University of Vienna, Vienna, Austria.
Laccone F; Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
Feucht M; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria. martha.feucht@meduniwien.ac.at.

Orphanet J Rare Dis ; 11(1): 145, 2016 11 03.

Article em En | MEDLINE | ID: mdl-27809914

Assuntos

Epilepsia/tratamento farmacológico; Everolimo/uso terapêutico; Esclerose Tuberosa/tratamento farmacológico; Adolescente; Criança; Pré-Escolar; Epilepsia/metabolismo; Everolimo/efeitos adversos; Feminino; Humanos; Imunossupressores/efeitos adversos; Imunossupressores/uso terapêutico; Lactente; Masculino; Estudos Prospectivos; Serina-Treonina Quinases TOR/metabolismo; Resultado do Tratamento; Esclerose Tuberosa/metabolismo

Palavras-chave

Child; Epilepsy; Everolimus; Tuberous sclerosis complex; mTOR

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esclerose Tuberosa / Epilepsia / Everolimo Tipo de estudo: Guideline / Observational_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Orphanet J Rare Dis Ano de publicação: 2016 Tipo de documento: Article

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