Is Pichia pastoris a realistic platform for industrial production of recombinant human interferon gamma?

Razaghi, Ali; Tan, Emilyn; Lua, Linda H L; Owens, Leigh; Karthikeyan, O P; Heimann, Kirsten

Razaghi, Ali; Tan, Emilyn; Lua, Linda H L; Owens, Leigh; Karthikeyan, O P; Heimann, Kirsten.

Afiliação

Razaghi A; College of Science and Engineering, James Cook University, Townsville 4811, Qld, Australia; Centre for Biodiscovery and Molecular Development of Therapeutics, James Cook University, Townsville 4811, Qld, Australia.
Tan E; The University of Queensland, Protein Expression Facility, Brisbane 4072, Qld, Australia.
Lua LHL; The University of Queensland, Protein Expression Facility, Brisbane 4072, Qld, Australia.
Owens L; College of Public Health, Medical and Veterinary Science, James Cook University, Townsville 4811, Qld, Australia.
Karthikeyan OP; Department of Biology, Hong Kong Baptist University, Hong Kong.
Heimann K; College of Science and Engineering, James Cook University, Townsville 4811, Qld, Australia; Centre for Biodiscovery and Molecular Development of Therapeutics, James Cook University, Townsville 4811, Qld, Australia. Electronic address: Kirsten.heimann@jcu.edu.au.

Biologicals ; 45: 52-60, 2017 Jan.

Article em En | MEDLINE | ID: mdl-27810255

Assuntos

Interferon gama/biossíntese; Pichia/metabolismo; Humanos; Interferon gama/genética; Pichia/genética; Proteínas Recombinantes/biossíntese; Proteínas Recombinantes/genética

Palavras-chave

Biopharmaceuticals; Interferon gamma; Low-abundance RNA; Minimum free energy; Pichia pastoris; Protein expression

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pichia / Interferon gama Limite: Humans Idioma: En Revista: Biologicals Ano de publicação: 2017 Tipo de documento: Article

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