Hemorheological parameters in patients with fibromyalgia syndrome.
Clin Hemorheol Microcirc
; 65(4): 309-315, 2017.
Article
em En
| MEDLINE
| ID: mdl-27814281
ABSTRACT
AIM:
To evaluate hemorheological parameters in patients with fibromyalgia syndrome (FMS) in order to elucidate the etiology of the disease.METHODS:
Twenty-three adult FMS patients and 20 healthy controls were enrolled in the study. Diabetics, hypertensives and those with any rheumatological disorder or use drugs or smoking cigarette were excluded from the study. Following parameters were analyzed in each subject; erythrocyte deformability, erythrocyte aggregation, plasma viscosity, complete blood count, fasting blood glucose, fibrinogen, albumin, globulin and lipid profile.RESULTS:
Erythrocyte elongation indices indicating deformability of erythrocytes were higher in FMS patients (0.564±0.002 at 16.87âmPa and 0.605±0.002 at 30âmPa shear rate) than controls (0.558±0.001 at 16.87âmPa and 0.600±0.003 at 30âmPa shear rate). Erythrocyte aggregation speed was higher in FMS patients (2.1±0.1âs) than controls (2.3±0.2âs). Erythrocyte aggregation index was also higher in FMS patients (65.5±1.3) than controls (62.9±1.5). Erythrocyte aggregation amplitude and plasma viscosity values were similar in both groups (both pâ>â0.05). Among the complete blood count and biochemical parameters, only albumin levels were lower in the FM patients than controls (pâ<â0.05).CONCLUSION:
Our results indicate higher erythrocyte deformability and quicker erythrocyte aggregation in FM patients.Palavras-chave
Texto completo:
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fibromialgia
/
Hemorreologia
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Clin Hemorheol Microcirc
Ano de publicação:
2017
Tipo de documento:
Article