Pharmacokinetics and pharmacodynamics study of rhein treating renal fibrosis based on metabonomics approach.

Sun, Hao; Luo, Guangwen; Xiang, Zheng; Cai, Xiaojun; Chen, Dahui

Sun, Hao; Luo, Guangwen; Xiang, Zheng; Cai, Xiaojun; Chen, Dahui.

Afiliação

Sun H; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Luo G; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Xiang Z; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China. Electronic address: XZH0077@126.com.
Cai X; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.
Chen D; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China.

Phytomedicine ; 23(13): 1661-1670, 2016 Dec 01.

Article em En | MEDLINE | ID: mdl-27823631

Assuntos

Antraquinonas/farmacocinética; Nefropatias/tratamento farmacológico; Nefropatias/patologia; Rheum/química; Animais; Biomarcadores/sangue; Cromatografia Líquida/métodos; Fibrose/tratamento farmacológico; Nefropatias/metabolismo; Masculino; Metabolômica/métodos; Ratos Sprague-Dawley; Espectrometria de Massas em Tandem

Palavras-chave

Metabolomics; Pharmacodynamic; Pharmacokinetic; Rhein; Rhubarb

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rheum / Antraquinonas / Nefropatias Limite: Animals Idioma: En Revista: Phytomedicine Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google