NFAT5 protects astrocytes against oxygen-glucose-serum deprivation/restoration damage via the SIRT1/Nrf2 pathway.

Xia, Xun; Qu, Bo; Li, Yun-Ming; Yang, Li-Bin; Fan, Ke-Xia; Zheng, Hui; Huang, Hai-Dong; Gu, Jian-Wen; Kuang, Yong-Qin; Ma, Yuan

Xia, Xun; Qu, Bo; Li, Yun-Ming; Yang, Li-Bin; Fan, Ke-Xia; Zheng, Hui; Huang, Hai-Dong; Gu, Jian-Wen; Kuang, Yong-Qin; Ma, Yuan.

Afiliação

Xia X; Department of Neurological Surgery, Chengdu Military General Hospital, Chengdu, 610083, China.
Qu B; Department of Orthopaedics, Chengdu Military General Hospital, Chengdu, 610083, China.
Li YM; Department of Neurological Surgery, Chengdu Military General Hospital, Chengdu, 610083, China.
Yang LB; Department of Neurological Surgery, Chengdu Military General Hospital, Chengdu, 610083, China.
Fan KX; Department of Neurological Surgery, Chengdu Military General Hospital, Chengdu, 610083, China.
Zheng H; Department of Neurological Surgery, Chengdu Military General Hospital, Chengdu, 610083, China.
Huang HD; Department of Neurological Surgery, Chengdu Military General Hospital, Chengdu, 610083, China.
Gu JW; Department of Neurological Surgery, The 306th Hospital of PLA, No. 9 Anxiangbeili, Chaoyang District, Beijing, 100101, China. jianwengubj@163.com.
Kuang YQ; Department of Neurological Surgery, Chengdu Military General Hospital, Chengdu, 610083, China. yongqinkuang@126.com.
Ma Y; Department of Neurological Surgery, Chengdu Military General Hospital, Chengdu, 610083, China. yuanma15@163.com.

J Mol Neurosci ; 61(1): 96-104, 2017 Jan.

Article em En | MEDLINE | ID: mdl-27838821

Assuntos

Astrócitos/metabolismo; Glucose/deficiência; Fator 2 Relacionado a NF-E2/metabolismo; Oxigênio/metabolismo; Traumatismo por Reperfusão/metabolismo; Sirtuína 1/metabolismo; Fatores de Transcrição/metabolismo; Animais; Apoptose; Hipóxia Celular; Células Cultivadas; Masculino; Fator 2 Relacionado a NF-E2/genética; Ratos; Ratos Sprague-Dawley; Sirtuína 1/genética; Medula Espinal/irrigação sanguínea; Medula Espinal/citologia; Medula Espinal/metabolismo; Superóxido Dismutase/genética; Superóxido Dismutase/metabolismo; Fatores de Transcrição/genética

Palavras-chave

Astrocytes; Nuclear factor of activated T cell 5; Nuclear factorE2-related factor 2; Oxygenglucoseserum deprivation/reoxygenation; Sirtuin 1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxigênio / Fatores de Transcrição / Traumatismo por Reperfusão / Astrócitos / Fator 2 Relacionado a NF-E2 / Sirtuína 1 / Glucose Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Mol Neurosci Ano de publicação: 2017 Tipo de documento: Article

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