Cell cycle arrest in the jewel wasp Nasonia vitripennis in larval diapause.
J Insect Physiol
; 106(Pt 2): 147-152, 2018 04.
Article
em En
| MEDLINE
| ID: mdl-27894937
ABSTRACT
Insects enter diapause to synchronise their life cycle with biotic and abiotic environmental conditions favourable for their development, reproduction, and survival. One of the most noticeable characteristics of diapause is the blockage of ontogeny. Although this blockage should occur with the cessation of cellular proliferation, i.e. cell cycle arrest, it was confirmed only in a few insect species and information on the molecular pathways involved in cell cycle arrest is limited. In the present study, we investigated developmental and cell cycle arrest in diapause larvae of the jewel wasp Nasonia vitripennis. Developmental and cell cycle arrest occur in the early fourth instar larval stage of N. vitripennis under short days. By entering diapause, the S fraction of the cell cycle disappears and approximately 80% and 20% of cells arrest their cell cycle in the G0/G1 and G2 phases, respectively. We further investigated expression of cell cycle regulatory genes and some housekeeping genes to dissect molecular mechanisms underlying the cell cycle arrest.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vespas
/
Pontos de Checagem do Ciclo Celular
/
Diapausa de Inseto
Limite:
Animals
Idioma:
En
Revista:
J Insect Physiol
Ano de publicação:
2018
Tipo de documento:
Article