A matrix of morphology and distribution of calcifications in the breast: Analysis of 849 vacuum-assisted biopsies.
Eur J Radiol
; 86: 221-226, 2017 Jan.
Article
em En
| MEDLINE
| ID: mdl-28027751
ABSTRACT
OBJECTIVE:
The purpose of this retrospective analysis was to evaluate the likelihood of malignancy in prospectively categorized BI-RADS 4 and BI-RADS 5 calcifications. MATERIAL ANDMETHODS:
This analysis included 849 women who underwent vacuum biopsy for BI-RADS 4 (with the subgroups 4A, 4B and 4C) or BI-RADS 5 calcifications between February 2007 and May 2015. Calcifications were classified according to the morphology and distribution descriptors of the BI-RADS lexicon (BI-RADS 4th edition lexicon). A standardized scheme (matrix) was used to combine the characteristics of the grouped calcifications with the BI-RADS assessment category.RESULTS:
Overall, 275/849 (32%) lesions were found to be malignant. 285/327/208/29 calcified lesions were prospectively classified as BI-RADS 4A/4B/4C/5 indicating a risk for malignancy of 16%/27%/55%/90%, respectively. The morphology descriptors predicted the risk for malignancy as follows typically benign (n=55) 2%; indeterminate (n=676) 27%; typically malignant (n=118) 80%. The distribution descriptors correlated with a malignant histology as follows diffuse (n=0); round or oval (n=261) 22%; regional (n=398) 33%; segmental (n=106) 42%; linear or branching (n=85) 55%. There was a significant difference between the descriptor categories (p<0.0001).CONCLUSION:
A standard scheme combining the morphology and distribution characteristics proved to be a helpful tool in diagnosis of calcifications, bridging the gap between description and classification of these lesions.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Mama
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Neoplasias da Mama
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Calcinose
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Middle aged
Idioma:
En
Revista:
Eur J Radiol
Ano de publicação:
2017
Tipo de documento:
Article