Validation of a Fragment-Based Profiler for Thiol Reactivity for the Prediction of Toxicity: Skin Sensitization and Tetrahymena pyriformis.

Ebbrell, David J; Madden, Judith C; Cronin, Mark T D; Schultz, Terry W; Enoch, Steven J

Ebbrell, David J; Madden, Judith C; Cronin, Mark T D; Schultz, Terry W; Enoch, Steven J.

Afiliação

Ebbrell DJ; School of Pharmacy and Bimolecular Sciences, Liverpool John Moores University , 3 Byrom Street, Liverpool L3 3AF, England.
Madden JC; School of Pharmacy and Bimolecular Sciences, Liverpool John Moores University , 3 Byrom Street, Liverpool L3 3AF, England.
Cronin MT; School of Pharmacy and Bimolecular Sciences, Liverpool John Moores University , 3 Byrom Street, Liverpool L3 3AF, England.
Schultz TW; Department of Comparative Medicine, College of Veterinary Medicine, The University of Tennessee , Knoxville, Tennessee 37996, United States.
Enoch SJ; School of Pharmacy and Bimolecular Sciences, Liverpool John Moores University , 3 Byrom Street, Liverpool L3 3AF, England.

Chem Res Toxicol ; 30(2): 604-613, 2017 02 20.

Article em En | MEDLINE | ID: mdl-28045255

Assuntos

Pele/efeitos dos fármacos; Compostos de Sulfidrila/toxicidade; Tetrahymena pyriformis/efeitos dos fármacos; Algoritmos; Animais; Relação Quantitativa Estrutura-Atividade; Compostos de Sulfidrila/química

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pele / Compostos de Sulfidrila / Tetrahymena pyriformis Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Chem Res Toxicol Ano de publicação: 2017 Tipo de documento: Article

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