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Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor.
Huang, Yuhui; Sumida, Mami; Kumazoe, Motofumi; Sugihara, Kaori; Suemasu, Yumi; Yamada, Shuhei; Yamashita, Shuya; Miyakawa, Jyunichi; Takahashi, Takashi; Tanaka, Hiroshi; Fujimura, Yoshinori; Tachibana, Hirofumi.
Afiliação
  • Huang Y; Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan. tatibana@agr.kyushu-u.ac.jp.
  • Sumida M; Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan. tatibana@agr.kyushu-u.ac.jp.
  • Kumazoe M; Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan. tatibana@agr.kyushu-u.ac.jp.
  • Sugihara K; Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan. tatibana@agr.kyushu-u.ac.jp.
  • Suemasu Y; Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan. tatibana@agr.kyushu-u.ac.jp.
  • Yamada S; Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan. tatibana@agr.kyushu-u.ac.jp.
  • Yamashita S; Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan. tatibana@agr.kyushu-u.ac.jp.
  • Miyakawa J; Department of Applied Chemistry, Graduate School of Science and Engineering, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro, Tokyo 152-8552, Japan.
  • Takahashi T; Yokohama College of Pharmacy 601, Matana-cho, Totsuka-ku, Yokohama, Kanagawa 245-0066, Japan.
  • Tanaka H; Department of Applied Chemistry, Graduate School of Science and Engineering, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro, Tokyo 152-8552, Japan.
  • Fujimura Y; Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan. tatibana@agr.kyushu-u.ac.jp.
  • Tachibana H; Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan. tatibana@agr.kyushu-u.ac.jp.
Chem Commun (Camb) ; 53(12): 1941-1944, 2017 Feb 07.
Article em En | MEDLINE | ID: mdl-28079202
ABSTRACT
Green tea polyphenol (-)-epigallocatechin-3-O-gallate (EGCG) has been attributed to the activation of its cell surface sensing receptor 67 kDa laminin receptor (67LR). However, the action of EGCG to activate 67LR remains unknown. Here we show that EGCG undergoes oligomer formation on its surface receptor 67LR.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Chá / Catequina / Receptores de Laminina / Antineoplásicos / Antioxidantes Limite: Humans Idioma: En Revista: Chem Commun (Camb) Ano de publicação: 2017 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Chá / Catequina / Receptores de Laminina / Antineoplásicos / Antioxidantes Limite: Humans Idioma: En Revista: Chem Commun (Camb) Ano de publicação: 2017 Tipo de documento: Article