Anti-Prion Screening for Acridine, Dextran, and Tannic Acid using Real Time-Quaking Induced Conversion: A Comparison with PrPSc-Infected Cell Screening.

Hyeon, Jae Wook; Kim, Su Yeon; Lee, Sol Moe; Lee, Jeongmin; An, Seong Soo A; Lee, Myung Koo; Lee, Yeong Seon

Hyeon, Jae Wook; Kim, Su Yeon; Lee, Sol Moe; Lee, Jeongmin; An, Seong Soo A; Lee, Myung Koo; Lee, Yeong Seon.

Afiliação

Hyeon JW; Division of Zoonoses, Center for Immunology & Pathology, National Institute of Health, Korea Centers for Disease Control and Prevention, Chungcheongbuk-do, Korea.
Kim SY; Division of Zoonoses, Center for Immunology & Pathology, National Institute of Health, Korea Centers for Disease Control and Prevention, Chungcheongbuk-do, Korea.
Lee SM; Division of Zoonoses, Center for Immunology & Pathology, National Institute of Health, Korea Centers for Disease Control and Prevention, Chungcheongbuk-do, Korea.
Lee J; Division of Zoonoses, Center for Immunology & Pathology, National Institute of Health, Korea Centers for Disease Control and Prevention, Chungcheongbuk-do, Korea.
An SS; Gachon BioNano Research Institute, Gachon University, Gyeonggi-do, Korea.
Lee MK; College of Pharmacy, Chungbuk National University, Cheongju, Korea.
Lee YS; Division of Zoonoses, Center for Immunology & Pathology, National Institute of Health, Korea Centers for Disease Control and Prevention, Chungcheongbuk-do, Korea.

PLoS One ; 12(1): e0170266, 2017.

Article em En | MEDLINE | ID: mdl-28095474

Assuntos

Acridinas/farmacologia; Síndrome de Creutzfeldt-Jakob/metabolismo; Demência/metabolismo; Dextranos/farmacologia; Neuroblastoma/metabolismo; Proteínas PrPSc/antagonistas & inibidores; Taninos/farmacologia; Anti-Infecciosos/farmacologia; Anticoagulantes/farmacologia; Encéfalo/efeitos dos fármacos; Encéfalo/metabolismo; Síndrome de Creutzfeldt-Jakob/tratamento farmacológico; Síndrome de Creutzfeldt-Jakob/patologia; Demência/tratamento farmacológico; Demência/patologia; Ensaios de Triagem em Larga Escala; Humanos; Neuroblastoma/tratamento farmacológico; Neuroblastoma/patologia; Proteínas PrPSc/metabolismo; Células Tumorais Cultivadas

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Taninos / Acridinas / Síndrome de Creutzfeldt-Jakob / Dextranos / Proteínas PrPSc / Demência / Neuroblastoma Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: PLoS One Ano de publicação: 2017 Tipo de documento: Article

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