[Experimental visualization of human colon cancer using 131I-antibodies to intestinal beta 1 MA antigen]. / Vizualizatsiia kartsinom tolstoi kishki cheloveka s pomoshch'iu 131I-antitel k kishechnomu antigenu beta 1 MA v éksperimente.

ABSTRACT

131I-antibodies to human beta 1 colonic antigen was administered i.v. to nude mice with transplanted human colon carcinoma. Injections were followed by mouse whole-body investigation with the help of gamma-camera and scanner. The distribution of radioactivity in murine tissues was investigated with a gamma-counter. Sharp images of tumor were obtained with the help of the gamma-camera and scanner. The results of visualization were in accord with radioimmunometric data. A conclusion was made of effective visualization of human colon carcinoma transplanted to nude mice using iodinated antibodies to specific beta 1 MA epithelial colonic antigen.