Biomarkers of oxidative stress in pregnancy complications.
Biomark Med
; 11(3): 295-306, 2017 Mar.
Article
em En
| MEDLINE
| ID: mdl-28157383
ABSTRACT
Pregnancy complications including pre-eclampsia, gestational-diabetes mellitus, preterm birth and intrauterine growth restriction can cause acute and chronic health problems for the mother and lead to fetal loss or dysregulation of infant physiology. The human placenta is susceptible to oxidative stress and oxidative damage in early gestation contributes to the onset of these conditions later in pregnancy. Current methods of predicting pregnancy complications are limited and although a large number of factors are associated with disease progression, few biomarkers have been used to aid in disease diagnosis early in gestation. This review discusses the detection of oxidative stress markers in biological fluids and highlights the need for further studies to validate their use in the prediction or diagnosis of pregnancy disorders.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pré-Eclâmpsia
/
Biomarcadores
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Diabetes Gestacional
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Estresse Oxidativo
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Retardo do Crescimento Fetal
Tipo de estudo:
Prognostic_studies
Limite:
Female
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Humans
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Pregnancy
Idioma:
En
Revista:
Biomark Med
Ano de publicação:
2017
Tipo de documento:
Article