Drugs in development for herpes simplex and varicella zoster virus.
Clin Pharmacol Ther
; 102(1): 30-32, 2017 07.
Article
em En
| MEDLINE
| ID: mdl-28160282
ABSTRACT
The alpha-herpesviruses varicella zoster virus (VZV) and herpes simplex virus (HSV) share common features including lifelong persistence in sensory ganglia and the risk of recurrences. For both HSV and VZV, standard-of-care (SoC) is based on nucleoside analogs (NAs), which require specific activation in infected cells. These existing drugs exhibit substantial limitations, warranting the development of new and more effective drugs.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Simplexvirus
/
Herpesvirus Humano 3
/
Herpes Simples
/
Herpes Zoster
Limite:
Humans
Idioma:
En
Revista:
Clin Pharmacol Ther
Ano de publicação:
2017
Tipo de documento:
Article