Isolation and Structure Elucidation of Glucosylated Colchicinoids from the Seeds of Gloriosa superba by LC-DAD-SPE-NMR.
J Nat Prod
; 80(4): 1187-1191, 2017 04 28.
Article
em En
| MEDLINE
| ID: mdl-28211687
ABSTRACT
Four new colchicinoids were isolated from the seeds of Gloriosa superba together with the known compounds colchicoside (4) and 3-de-O-methylcolchicine-3-O-ß-d-glucopyranosyl-(1â4)-3-O-ß-d-glucopyranoside (6), by means of conventional column chromatography and LC-DAD-SPE-NMR. The new compounds were identified as N-deacetyl-N-formyl-3-de-O-methylcolchicine-3-O-ß-d-glucopyranoside (1), 3-de-O-methylcolchicine-3-O-ß-d-glucopyranosyl-(1â6)-3-O-ß-d-glucopyranoside (2), N-deacetyl-N-formyl-3-de-O-methylcolchicine-3-O-ß-d-glucopyranosyl-(1â6)-3-O-ß-d-glucopyranoside (3), and 3-de-O-methylcolchicine-3-O-ß-d-glucopyranosyl-(1â3)-3-O-ß-d-glucopyranoside (5). The structure elucidation was performed by means of NMR (COSY, HSQC, and HMBC), HRESIMS/MS, and GCMS data analysis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Saponinas
/
Sementes
/
Colchicina
/
Colchicaceae
/
Glicosídeos
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Nat Prod
Ano de publicação:
2017
Tipo de documento:
Article