Divergence Palsy due to Divalproex and Oxcarbazepine.
Clin Neuropharmacol
; 40(3): 154-155, 2017.
Article
em En
| MEDLINE
| ID: mdl-28277442
ABSTRACT
OBJECTIVE:
This case series is the first to describe divergence palsy as an adverse effect of antiepileptic drug use. Diplopia is a common adverse effect of antiepileptic drugs, but no explanatory motility deficit has ever been reported.METHODS:
We present 2 patients, 1 on oxcarbazepine and 1 on divalproex, each with a normal examination result between spells and divergency palsy when symptomatic.RESULTS:
Discontinuation of the antiepileptic medication led to resolution of the episodes in both cases. Rechallenge with the offending agent after washout in one patient resulted in recurrence of diplopia and divergence palsy, both resolving after subsequent withdrawal of the antiepileptic.CONCLUSIONS:
Antiepileptic drugs may cause divergence palsy.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
Base de dados:
MEDLINE
Assunto principal:
Carbamazepina
/
Doenças do Nervo Oculomotor
/
Ácido Valproico
/
Síndromes Neurotóxicas
/
Anticonvulsivantes
Tipo de estudo:
Etiology_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
En
Revista:
Clin Neuropharmacol
Ano de publicação:
2017
Tipo de documento:
Article