A metabolomic evaluation of the phytochemical composition of tomato juices being used in human clinical trials.
Food Chem
; 228: 270-278, 2017 Aug 01.
Article
em En
| MEDLINE
| ID: mdl-28317724
ABSTRACT
Juices from the traditional red tomato and a unique tangerine tomato variety are being investigated as health promoting foods in human clinical trials. However, it is unknown how the tangerine and red tomato juices differ in biologically relevant phytochemicals beyond carotenoids. Here liquid-chromatography high-resolution mass spectrometry metabolomics was used to evaluate broadly the similarities and differences in carotenoids and other phytochemicals between red and tangerine tomato juices intended for clinical interventions. This untargeted approach was successful in the rapid detection and extensive characterization of phytochemicals belonging to various compound classes. The tomato juices were found to differ significantly in a number of phytochemicals, including carotenoids, chlorophylls, neutral lipids, and cinnamic acid derivatives. The largest differences were in carotenoids, including lycopene, phytoene, phytofluene, neurosporene, and ζ-carotene. Smaller, but significant, differences were observed in polar phytochemicals, such as chlorogenic acid, hydroxyferulic acid, phloretin-di-C-glycoside, and isopropylmalic acid.
Palavras-chave
Carotenoids; Chlorogenic acid (PubChem CID: 1794427); Flavonoids; LCMS; Lycopene (PubChem CID: 446925); Metabolomics; Naringenin (PubChem CID: 932); Neurosporene (PubChem CID: 5280789); Phytochemicals; Phytoene (PubChem CID: 5280784); Phytofluene (PubChem CID: 6436722); Rutin (PubChem CID: 5280805); Tomatoes; α-Tomatine (PubChem CID: 28523); ζ-Carotene (PubChem CID: 5280788)
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Espectrometria de Massas
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Bebidas
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Flavonoides
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Cromatografia Líquida
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Solanum lycopersicum
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Metabolômica
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Compostos Fitoquímicos
Limite:
Humans
Idioma:
En
Revista:
Food Chem
Ano de publicação:
2017
Tipo de documento:
Article