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PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation.
Wu, Rui; Sanishvili, Ruslan; Belitsky, Boris R; Juncosa, Jose I; Le, Hoang V; Lehrer, Helaina J S; Farley, Michael; Silverman, Richard B; Petsko, Gregory A; Ringe, Dagmar; Liu, Dali.
Afiliação
  • Wu R; Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, IL 60660.
  • Sanishvili R; GM/CA@APS, The X-Ray Science Division, the Advanced Photon Source, Argonne National Laboratory, Lemont, IL 60439.
  • Belitsky BR; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111.
  • Juncosa JI; Department of Chemistry, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Northwestern University, Evanston, IL 60208-3113.
  • Le HV; Department of Molecular Biosciences, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Northwestern University, Evanston, IL 60208-3113.
  • Lehrer HJ; Department of Chemistry, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Northwestern University, Evanston, IL 60208-3113.
  • Farley M; Department of Molecular Biosciences, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Northwestern University, Evanston, IL 60208-3113.
  • Silverman RB; Department of Biochemistry, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454.
  • Petsko GA; Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, IL 60660.
  • Ringe D; Department of Chemistry, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Northwestern University, Evanston, IL 60208-3113.
  • Liu D; Department of Molecular Biosciences, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Northwestern University, Evanston, IL 60208-3113.
Proc Natl Acad Sci U S A ; 114(15): 3891-3896, 2017 04 11.
Article em En | MEDLINE | ID: mdl-28348215
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfato de Piridoxal / Bacillus subtilis / Proteínas de Bactérias / Regulação Bacteriana da Expressão Gênica / Ácido gama-Aminobutírico Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfato de Piridoxal / Bacillus subtilis / Proteínas de Bactérias / Regulação Bacteriana da Expressão Gênica / Ácido gama-Aminobutírico Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2017 Tipo de documento: Article