The Development of Translational Biomarkers as a Tool for Improving the Understanding, Diagnosis and Treatment of Chronic Neuropathic Pain.

Buckley, David A; Jennings, Elaine M; Burke, Nikita N; Roche, Michelle; McInerney, Veronica; Wren, Jonathan D; Finn, David P; McHugh, Patrick C

Buckley, David A; Jennings, Elaine M; Burke, Nikita N; Roche, Michelle; McInerney, Veronica; Wren, Jonathan D; Finn, David P; McHugh, Patrick C.

Afiliação

Buckley DA; Centre for Biomarker Research and Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, HD1 3DH, UK.
Jennings EM; Pharmacology and Therapeutics, National University of Ireland, Galway, Ireland.
Burke NN; Centre for Pain Research and Galway Neuroscience Centre, National University of Ireland, Galway, Ireland.
Roche M; Pharmacology and Therapeutics, National University of Ireland, Galway, Ireland.
McInerney V; Centre for Pain Research and Galway Neuroscience Centre, National University of Ireland, Galway, Ireland.
Wren JD; Physiology, School of Medicine, National University of Ireland, Galway, Ireland.
Finn DP; Centre for Pain Research and Galway Neuroscience Centre, National University of Ireland, Galway, Ireland.
McHugh PC; Physiology, School of Medicine, National University of Ireland, Galway, Ireland.

Mol Neurobiol ; 55(3): 2420-2430, 2018 03.

Article em En | MEDLINE | ID: mdl-28361271

Assuntos

Dor Crônica/diagnóstico; Dor Crônica/genética; Marcadores Genéticos/genética; Neuralgia/diagnóstico; Neuralgia/genética; Biossíntese de Proteínas/genética; Animais; Dor Crônica/terapia; Humanos; Dor Lombar/diagnóstico; Dor Lombar/genética; Dor Lombar/terapia; Masculino; Neuralgia/terapia; Células do Corno Posterior/metabolismo; Células do Corno Posterior/patologia; Ratos; Ratos Sprague-Dawley; Inibidor Tecidual de Metaloproteinase-1/biossíntese; Inibidor Tecidual de Metaloproteinase-1/genética; Resultado do Tratamento

Palavras-chave

Back pain; Biomarker; Dorsal horn; Inflammatory pain; Neuropathic pain; Plasma

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biossíntese de Proteínas / Marcadores Genéticos / Dor Crônica / Neuralgia Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Mol Neurobiol Ano de publicação: 2018 Tipo de documento: Article

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